Addissie, Adamu (PhD)Gurmamo, Markos2018-09-182023-11-052018-09-182023-11-052014-06http://etd.aau.edu.et/handle/123456789/11970Back Ground: Malaria is Mosquito vector borne blood parasitic Disease and One of the major Health problems of humankind. Even though intensive control measure like vector control, environmental management through community participation, malaria disease remained public Health concern of our country. Unusual Malaria cases increment was reported from Le-Zembara kebele, Tembaro district, Kembata Tembaro Zone, SNNPR, Ethiopia, in January 2016. We investigated the outbreak to describe the Magnitude of the disease and identify the risk factors associated with the outbreak. Method: Microscopic and RDT laboratory investigation conducted to confirm the disease. Person, place and time describe the disease magnitude. The threshold of the malaria disease in this kebele is compared by using the previous same season case data. We conducted the case control study with randomly selected 44 cases and 88 unmatched community controls. Epi Info 7.1.4 and Microsoft Excel were used to perform data entry and analysis. We also assessed environmental risk factors for the outbreak. Previous years’ malaria data was received to establish threshold level and understand trends of the disease. We conducted case control study randomly selected 44 cases unmatched 88 community controls from the community. Result: - A total of 659 confirmed malaria cases (Attack Rate: 106 per 1000) and zero death were reported from January to February 2016 with the peak in February. Slide positivity rate was 77.8 %. Above 4 years age group were more affected by malaria (Age specific attack rate of per population was 121). Using bed net every night was preventive effect for the disease (Odds Ratio: 0.6, 95%CI, and 0.7-1.4). Presence of stagnant water (Odds Ratio: 6.2, 95%CI 1.5-24.8), presence of intermittent rivers in the area is (Odds of 1.6, 95%, 0.7-3.3 were associated with the disease occurrence. Conclusion and Recommendation:- Presence of stagnant water bodies near living area , Low utilization of Insecticide treated bed nets in the households and staying more time outside during night time are most associated factors for this malaria disease outbreak .Kebele was not 2 | P a g e ( B O W , M a r k o s G u r m a m o K a l o r e ) J u n e , 2 0 1 7 . sprayed with IRS (Propecxure chemical) since 12 months. We recommend the draining of stagnant water bodies, Proper Utilization of ITNs, and spray of IRS FOR households. Key Words: Malaria, Outbreak, Case-Control, Le-Zembara, Ethiopia.enMalaria, Outbreak, Case-Control, Le-Zembara, Ethiopia.Thesis