Mekonnen AbebayehuEmebet Demie2025-09-052025-09-052024-08https://etd.aau.edu.et/handle/123456789/7391Securidaca lonpeduculata is a well-known medicinal plant in the family of polygalaceae.The plant is locally known as “Itsemenahi’’ Amharic and “temenayi’’ in Afanoromo. It is traditionally used in headache, fever, epilepsy, asthma and cough. The different parts of S. longipeduculata have different purpose, in different countries, for example the root of this plant is used for treatment of fever, malaria, toothache in Nigeria, the leaves are used for treatment of headache skin infection in Nigeria and the steam bark is used for skin disease in Burkina Faso. Phytochemical investigation on the leaves of this plant resulted in the isolation of two compounds (SLE-6andSLE-7). Compound SLE-6 is flavonoid glycoside, compound SLE-7 is a group of galotannins namely: 1. Quercetine-3-O-L-arabinopyranoside. 2.1,5-Anhydro-D-glucitol Structural elucidations of those compounds are based on UV, 1D NMR (1H, 13C &DEPT-135) and 2D NMR (COSY, HSQC &HMBC) spectroscopic data obtained in comparison with similar compounds isolated from the plant.en-USPhytochemical InvestigationlongipedunculataSecuridaca LonpeduculataThesis