Eshetu, Eskinder(PhD)Getachew,Nardos2024-04-232024-04-232023https://etd.aau.edu.et/handle/123456789/2820Introduction: The electronic Health Commodity Management Information System (e- HCMIS), also known as DAGU, was developed locally to help in improving the health commodity supply chain in Ethiopia. However, there is paucity of information on the acceptability of the system for the end users. Objective: To investigate pharmacy professionals’ acceptance of the e-HCMIS and identify its determinants in public hospitals of Addis Ababa. Methods: A facility-based cross-sectional descriptive study, following a sequential explanatory mixed method approach with both qualitative and quantitative methods of data collection, was done. The study included 10 public hospitals in Addis Ababa. The quantitative approach used structured questionnaire based on extended Technology Acceptance Model 3 (TAM-3). Key informant interviews were done to clarify and contextualize the quantitative findings. Structural equation modeling with maximum likelihood estimation were used to analyze quantitative data. Qualitative interviews were thematically evaluated. Results: There were a total of 237 survey respondents, response rate of the study was 96.19%. TAM-3 explained 49.2% of the variance of behavioral intention to use e-HCMIS. The study found that Perceived Usefulness and Perceived ease of use were significant predictors of behavioral intention. Job relevance was a predominant factor for perceived usefulness; perceived enjoyment and computer anxiety were predominant factor for perceived ease of use. The qualitative study revealed perceived usefulness, management support, ownership and perceived ease of use were the major determinants of behavioral intention. iii Conclusion and Recommendation: Given the importance of perceived usefulness and perceived ease of use, including a more user friendly design and scaling up the level of application of the system are recommendeden-USe-HCMISDAGUdigitalizationacceptancetechnology acceptance modelThesis