Mahlet YigeremuEskinder KebedeMezgebu Gietnet2026-02-232026-02-232024-10-18https://etd.aau.edu.et/handle/123456789/7682Background: Heart disease affects between 1% and 4% of pregnancies and continues to be a leading cause of maternal death worldwide, affecting women in both high income and low- to middle-income countries. The maternal mortality rate due to cardiac conditions is approximately 9% in developed nations and 36% in developing regions. However, there is limited research in Ethiopia to fully understand the impact of heart disease on pregnant women and its effect on maternal outcomes. Objective: The purpose of this research is to evaluate how cardiac disease affects maternal outcomes in women with heart conditions during labor, delivery, and the postpartum period up until they are discharged from the hospital. The ultimate goal is to enhance their health and overall well-being. Methods: The study retrospectively enrolled 92/127 women with cardiac illness, who received labor and delivery service at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia, from Jan 1st, 2021 to Dec 31, 2023. Census sampling method was applied to include study participants. The data entered and analyzed using Epi-info version 7.0 and SPSS version 25.0. Bivariable regression done and variables with p-value ≤ 0.25 analyzed with multivariable logistic regression with a level of significance <0.05. Results: In this study, 92 participants that fulfill the inclusion criteria were enrolled following review of their medical charts. Majority of the study participants (65.2%) found in the age group of 25-34 years with mean ±SD of 28.1±5.2. Almost one-third of the participants were primiparous and 63% were from the rural area. This study shows the significant cause of heart disease is acquired causes (84.8%, n=78). Majority of patients (40.2%, n=37) have a functional status of NYHA class II. Mitral valve is the most commonly affected valve with 80.5% (n=74) contribution. Majority (46.7%, n=43) of deliveries were via operative vaginal deliveries and 34.8% (n=32) were delivered via C/S. Composite adverse maternal outcome was found in 28%, (26/92) participants. Heart failure and pulmonary edema were the two most common acute cardiac events each contributing 10.9% respectively.encardiac diseasematernal outcomeEthiopiaThesis