Dr.Mekonin, Desalew (Cardiologist and associate professor of internal medicine at AddisAbaba University)Teshome, Gemechis2021-02-072023-11-052021-02-072023-11-052020-12http://etd.aau.edu.et/handle/123456789/25011INTRODUCTION Heart failure (HF) is a complex clinical syndrome resulting from structural and functional impairment of ventricular filling or ejection of blood. It is one of the major public health problems worldwide.It is one of major public health problem worldwide. Acute Heart failure is broadly defined as a rapid onset of new or worsening signs and symptoms of HF. Most of registries done in the developed world showed it is more common in elderly male, 66-75% of the patients has history of HF. In Sub Saharan African countries, Unlike developed nations; the most prevailing causes of HF in Africans remains largely non-ischemic, patients tend to be younger and most likely to present with severe symptoms. In Ethiopia, there are few hospital-based studies done. One retrospective chart review done at the University of Gonder showed of 311 patients; HFpEF is more common (52.73%) and tends to be women (76.22%). They predominantly had etiologies of valvular and hypertensive heart diseases.Another prospective study done at TASH showed; among 128 patients, 75 (58.6%)female, CRVHD was the most common (52.3%).A recent prospective study done at showed: median age of 34 years. The leading precipitating factor and underlying disease at the time of admission were pneumonia (47.5%) and chronic rheumatic heart disease (48.5%), respectively. In hospital, mortality was found to be 17.2%. In this retrospective chart review 259 patients charts was revied of which 33 patients were died and 226 were discharged improved. Mean age was 39 years and CRVHD was the commonest cause of AHF. With regards to comorbidity Hypertension and DM was associated with it in 25.5% and 19.7% of the cases. AF and CAP was the commonest identified precipitating factors. Low Hgb, lowsodium ,low potassium and increased creatine were predictors of mortality.en-USHeart Failure, adult patientsThesis