Tariku Dejene (Ass. Professor)Fasil Alene2024-06-032024-06-032022-06https://etd.aau.edu.et/handle/123456789/3103Sexually transmitted diseases are major cause of infertility, acute illness, long-term disability and death in both developed and developing country. Preventing and controlling STDs will have reducing bad pregnancy outcomes and women’s risk of cervical cancer, infertility and chronic pelvic inflammatory disease and an attempt has been made to assess knowledge, attitudes, risky behavior and preventive practices on sexually transmitted diseases among high school adolescents in Addis Ababa. Ethiopia. School based cross sectional study was conducted among 419 students and stratified random sampling technique was used in proportion to number of school and finally, the respondents were selected by simple random sampling in proportion of grade and sex. Semi structured questionnaire was used to collect information from respondents and data was entered and analyzed using SPSS Version 20 software. The descriptive results were presented by table and chart, and logistic regression analyses were used to identify associated factors and to measure the association of outcome variables. From 419 randomly selected adolescent students 409 of them participated in the study which gives a response rate of 97% and majority 337 (82.4%) of students were from Government Schools and the rest 72 (17.6%) were from Private Schools. Mean (+SD) and median age for the respondents were found to be 17.03 (+1.457) and 17 years respectively. 87.3% of students had good knowledge of STDs but more than half of the participants (64.1%) never knew STDs other than HIV/ AIDS. About half (50.4%) of respondents had appropriate attitude and more than half (68.7%) of respondents had good preventive Practice towards STDs but students who practiced sexual intercourse ever had 99% less likely to have good preventive practice than who never had sex (AOR: .011, 95% CI (0. 004, .030)). The odds of having risky sexual experience among Students who have appropriate knowledge on STDs were decline by 82% than those students who haven’t appropriate knowledge on STDs (AOR: 0.182,95% CI(.044,.756)).enSexually transmitted diseaseknowledgeattituderisky behavior and preventive practice.Thesis