Habte,Teshome (Ass. Prof.),Hailu,Aklil(Ass. Prof.)Beyene,Abdisa2024-04-232024-04-232023https://etd.aau.edu.et/handle/123456789/2830Background: Achieving the recommended LDL-C goal is vital for managing cardiovascular risk. However, research on LDL-C goal achievement and associated factors in Sub-Saharan Africa, particularly in Ethiopia, is limited. While global rates vary from 18% to 73%, there is a need for further investigation in this region to better understand and address the factors influencing LDL-C goal attainment. Objective: To evaluate low-density lipoprotein cholesterol goal achievement and associated factors among type 2 diabetes patients at Tikur Anbessa Specialized Hospital in Addis Ababa, Ethiopia. Methods and Material: In a cross-sectional study at Tikur Anbessa Specialized Hospital, 338 patients diagnosed with type 2 diabetes from the diabetic follow-up clinic were included. The participants were selected using systematic random sampling. Data was collected using a pretested, structured questionnaire and analyzed using Epi info version 7.2 and SPSS version 25. Bivariate and multivariable logistic regressions were performed to examine the association between variables. Adjusted odds ratios (AOR) with 95% confidence intervals were calculated, and a p-value of ≤0.05 was considered statistically significant for associations between independent and outcome variables. Result: The LDL goal achievement among type II diabetes patients is 58.9%.Total triglyceride level (AOR=0.19, 95%CI, 0.12, 0.54, P= <0.0001), history of smoking (AOR=0.198, 95%CI, 1.06, 1.10, P=<0.0001), 40-65 years of age (AOR=0.21, 95%CI, 0.05, 0.87, P= 0.03), BMI (AOR=0.19, 95%CI, 0.12, 0.54, P= <0.0001)., were found to be statistically significant independent predictors for LDL Goal Achievement in type II Diabetes patients. Conclusion and recommendation: A study at Tikur Anbessa Specialized Hospital found that LDL-C goal achievement among Type 2 diabetes patients was acceptable but did not meet international standards. Factors like total triglyceride levels, smoking history, older age, and increased BMI influenced LDL-C goal achievement. It is important to raise awareness among healthcare professionals and patients about managing LDL-C levels in Type 2 diabetes. The Ministry of Health should prioritize interventions targeting total triglyceride levels and implement education campaigns. Healthcare professionals can optimize patient counseling and adhere to evidence-based guidelines for managing hypertriglyceridemia. Further research should explore additional factors like socio-economic status and comorbiditiesen-USLow-density lipoprotein cholesterol, statin, goal achievement, type 2 diabetesThesis