Gebreyohannis,Tigistu (Ass. Prof.),Mulugeta,Feven(BSc, MSc)Tefera,Shimeles2023-12-132023-12-132023http://etd.aau.edu.et/handle/123456789/881Background: Diabetic ketoacidosis (DKA) is one of the most severe clinical features of diabetes mellitus, which can result in morbidity and mortality. The prevalence of DKA is increasing worldwide and nationwide. There is a discrepancy of time to recovery from DKA between developed and developing country. The Ethiopian government aims to decrease premature mortality from noncommunicable diseases, including diabetes, by one-fourth by 2025. To achieve this target plan, more research should be conducted in this area. Objective: To assess time to recovery from DKA and its predictor among children with diabetic ketoacidosis at selected governmental hospitals in Addis Ababa, Ethiopia, 2023 Methods: A five years retrospective follow-up study design was employed among 391 children admitted with DKA to selected governmental hospitals in Addis Ababa, Ethiopia from January 1, 2018 to December 30, 2022. Simple random sampling technique was used to select the hospitals and participants. Preliminary survey of the study hospitals was done to determine flow and the sample was proportionally allocated. Structured data collection checklist was adapted from similar studies in the literature. Data was checked for completeness, and exported into Stata version 16 for analysis. A variable with P value < 0.05 in the multivariate Cox proportional hazards model was considered as significant predictors of time to recovery from DKA. Results: a total of 391 (92.4%) children with DKA were included in the final analysis. Out of these 370, recovered and discharged. The left 21 cases were censored. The overall median time taken for resolution of DKA was 27hrs, IQR (16-38). DM history (AHR=0.41, 95% CI:0.30-0.56), severity of DKA (AHR=2.35, 95% CI:1.36-4.1), presence of comorbidity (AHR=1.76, 95% CI:1.37-2.26), and blood sugar level were (AHR= 0.61, 95% CI:0.39-0.96) all independent predictors of time to recovery from DKA. Conclusion: Though the total median time to recovery from DKA was in the accepted range (<36hrs), it was significantly associated by the identified predictors in this study. Thus, increasing public awareness on symptoms of DKA, giving emphasis, enhancing quality of care, prioritize and treating children with identified predictors is important.en-USDiabetes, diabetic ketoacidosis, recovery time, childrenTime to recovery from diabetic ketoacidosis and its predictors among children with type 1 diabetes at selected governmental hospitals in Addis Ababa, Ethiopia, 2023: retrospective follow-up studyThesis