Wakgari Deressa(PhD, Prof.)Amanuel Arota2023-12-132023-12-132023-06-21http://etd.aau.edu.et/handle/123456789/873Chronic kidney disease is type of progressive kidney disease that mainly attributed to diabetes. Ethiopia is one of the developing countries with high incidence of chronic kidney disease among diabetes mellitus patients. However, little is known related to the incidence and predictors of chronic kidney disease among diabetes mellitus patients in Ethiopia. Objective: The main objective of this study was to determine incidence and predictors of chronic kidney diseases among diabetes mellitus patients in Wolaita Sodo Town, Southern Ethiopia. Methods: A health facility based retrospective follow-up study was conducted among 495 diabetes mellitus patients in Wolaita Sodo Town during March to May 2023. Simple random sampling technique was used to select individuals. A pre-tested structured data extraction toolwas used to collect data from patient’s chart using open data kit (ODK). Data were exported to STATA V17 software and cleaned for analysis. The mean and median were used to describe continuous variable. The Kaplan Meir curve along with log rank test was used to estimate and compare survival time. The cox hazard proportional hazard model with p value <0.05 was used to declare significance of association. Assumption was checked using Schoenfeld residual test. Result: The cumulative incidence of chronic kidney among diabetes mellitus patients and the incidence density is 14.9% (95CI%12-18.03) and 2 cases per 100 person years respectively. The median survival time wa 130 months (IQR128, 133). History of cardiovascular disease [adjusted hazard ratio (AHR) =2.12, 95%CI 1.16, 3.87], diabetic retinopathy [AHR= 1.86 95%CI 1.03–3.36], and acute kidney injury [AHR= 2.49, 95%CI 1.37, 4.54] was associated with higher risk of chronic kidney diseases. However, high density lipoprotein cholesterol ≥ 40 mg/dl was associated with lower risk of chronic kidney disease [AHR= 0.537, 95%CI 0.303, 0.0.95]. Conclusion: Incidence of chronic kidney disease among diabetes has become significant public health problem. Diabetes patients having baseline low level high density lipoprotein, developed diabetic retinopathy, had history cardiovascular disease, patients developed acute kidney injury were at high risk to the incidence of chronic kidney disease compared to their counter parts. Thus appropriate health interventions should be implemented to prevent and control the disease.en-USChronic kidney disease, cox proportional hazard model, retrospective study, EthiopiaThesis