Ayalew, Yohannes(Ass. Prof.)Dugassa, BokaKelbessa, Megertu2024-06-122024-06-122023https://etd.aau.edu.et/handle/123456789/3165Background:There has been a paradigm shift in health service delivery to a more holistic approach, which considers Health Related Quality of Life (HRQoL) and overall functioning. HRQoL is a multidimensional construct that encompasses physical functioning as well as psychosocial aspects of emotional and social functioning. Childhood Leukemia is among threats to HRQoL to the patients and parents of the children, which trigger extensive studies on the subject. Objective:The study objectives were twofold. Primarily, the statuses of HRQoL of childhood leukemia patients in TASH were assessed. Secondly, factors affecting HRQoL among childhood leukemia patients in TASH were examined. Method:The study employed mixed research approach where descriptive design and explanatory research design concurrently utilized. Questionnaire distributed to sample of 422 respondents with 100% response rate. Data were analyzed through descriptive analysis, regression analysis and correlation analysis. Result:The study revealed that, f 422 patients (57% males) with leukemia; their ages ranged from 5 to 14 year (Mean = 8.58, Standard Deviation = 2.56). Age and gender had a significant and positive relationship with HRQoL of childhood leukemia in TASH. Male children were found to be more exposed to the disease, while an increase image improves physical functioning aspect HRQoL. Addiction free habit of parents had a positive relationship with HRQoL and school functioning at p < 0.05. Chemotherapy morbidity however worsens physical wellbeing of the patients. All other correlations were statistically non-significant. The current findings added to HRQoL research, and provided an impetus for more research in the area of HRQoL for children with leukemia in Ethiopiaen-USHealth Related Quality of Life, Childhood LeukemiaThesis