Assefa, Teklegiorgis(Associate Professor)Nega, Mekuwanint2018-10-292023-11-042018-10-292023-11-042017-06http://etd.aau.edu.et/handle/123456789/13353The challenges of pharmaceutical supply chain developing an objective of challenges leading to stock out and what challenges are affecting the pharmaceutical supply chain activities for minimize the interruption of supplies that was important for health facility. Tracking challenges of the pharmaceutical supply chain is important. The aim of this study was to assess the pharmaceutical supply chain system of health centers and hospitals in Addis Ababa. The research conducted using both quantitative and qualitative approach of research methods and descriptive types of research using structured questionnaire collected data from sampled Addis Ababa health centers and hospitals. There are different challenges of pharmaceutical supply chain that lead for the stock outs. Integration of pharmaceuticals were no full supply from suppliers, forecasting disorganization for demand estimation, procurement poor coordination and there was stock out at least 12 months were high. LMIS was uncoordinated, no enough space of store capacity and problem of transportation those factors contribute for the stock out of pharmaceuticals. In pharmaceutical supply chain activities have different challenges for decreasing the interruption of pharmaceuticals. Challenges related to pharmaceutical supply integration of the health facility and the suppliers and planning the goals with suppliers and managing the supplier relation and develop capacity of supply planning from the production or manufacturer to the end user to facility. Forecasting process and acquiring of the pharmaceutical from the supplier in the requested quantity were challenging for the health facility and some information of the supply pipe line was not monitored and does not known so the probability of stock out were high. Decrease wastage of pharmaceuticals and prevent stock out in health facility it was one area of challenging that stock outs are occurred and emergency orders were placed decreasing those challenges increase the availability of pharmaceutical. Minimizing challenges of pharmaceutical activities of the supply chain improves the consistence of pharmaceutical supplies and decreases interruption of services in the health facilityenpharmaceutical stock outpharmaceutical supply chain activitieschallenges of pharmaceutical supply chainThesis