Deressa, Wakgary(PhD)Tamiru, AfeworkAstatke, Zemedkn2018-07-272023-11-052018-07-272023-11-052016-05http://etd.aau.edu.et/handle/123456789/10256Abstract Introduction Measles is an acute highly contagious viral disease. The sign and symptom of the disease includes Fever with maculo popular rash, one of the conjunctivitis, coryza (runny nose), and cough. Especially it is highly communicable during the first 8 days which is 4 days before rash and 4 days after rash. It affects mostly children and all people is susceptible unless develop immunity the virus is transmitted via droplets from the nose, mouth or throat of infected persons through coughing, sneezing or close personal contact or direct contact with infected secretions. Measles is a leading vaccine preventable contagious infectious disease caused by a paramyxovirus of the genus Morbilli. Methods By WHO standard case definition defined a confirmed Measles case as an illness characterized by acute onset of generalized maculopapular rash, fever, arthralgia, lymphadenopathy, conjunctivitis including Lab result update serum test result 2015 for Measles immunoglobulin M (IgM) antibody in the blood specimen already collected from cases (7) samples for laboratory confirmation. We conducted un-matched case control study to identify possible risk factors and mode of transmission. Result A total of 171 (95 %) of mother, 7 (3.9 %) father and 2 (1.1) controls introduced to interview the data interred and analyzed by excel sheet and eip-info 7 .A total of 5 blood samples were taken to lab exam 3 case are IGM positive which indicates there in confirmed measles epidemic in the woreda. Conclusion Lack of accessibility to routine vaccination and loss potency of vaccination cold chain contributes the more for epidemic and unvaccinated children accumulate in the area throughout many yeas leads to lack of heard immunity. Key Words Measles, measles outbreak “HABAFATU”enMeaslesMeasles outbreak “HABAFATU”Thesis