Engida GirmaAzeb Solomon2025-08-122025-08-122024-02-23https://etd.aau.edu.et/handle/123456789/6468Background: Depression is a prevalent mental health illness that significantly affects sexual function in both men and women. The purpose of this study was to investigate how common sexual dysfunction is in people with depressive illnesses and factors that are contributing to it. Methods: A cross sectional study with a sample size of 385 was carried out using consecutive sampling. The information was gathered using a structured questionnaire. Socio demographic questioners, CSFQ and clinical information extraction tool was employed in combination to determine sexual dysfunction prevalence and associated factors. SPSS version 26 was used to enter, clean and run statistical analysis. Results: majority were female (58.7%), aged 18-30 (40%), and married (46.5%). Occupational diversity included 34% in private work and 27.8% employed. Educational attainment was high (91.9% attended school, 47% completed high school). Among the depressive disorders, most participants were diagnosed with major depressive disorder (86%) and took medications, with fluoxetine (61.1%) and amitriptyline (25.1%) common. Sexual dysfunction prevalence was higher in males (88.7%) than females (81.4%), with pleasure, desire, orgasmic and arousal disorder prevalent in males and pleasure and arousal disorders in females. Factors like age, sex, occupation, living arrangement, marital disharmony/relational problem and comorbid medical conditions showed significant associations. Conclusion: The study finds that a significant proportion of individuals with depressive illnesses have sexual problems, with notable gender differences and associated factors such as age, sex, occupation, living arrangement, marital disharmony/relational problem and comorbid medical conditions. For a more successful and inclusive approach, integrating open and non-judgmental discussions about sexual health into routine psychiatric evaluations, tailoring interventions based on socio-demographic factors and recognizing the bidirectional link between depression and sexual dysfunction, while considering cultural influences is recommended.en-USSexual Dysfunction in PatientsThesis