Dr.Nega, Birhanu(Associate professor)Abagero, Abdulnasir(MPH, Resident Advisor Field Epidemiology program)Meded, Semira2021-05-302023-11-052021-05-302023-11-052021-02http://etd.aau.edu.et/handle/123456789/26592Introduction: As the COVID-19 pandemic is rapidly spreading throughout the world it has taken millions of lives. Among the population the critically ill and those who have other co morbidities are largely affected by it. In order to accommodate the growing number of critically ill patients and those who require mechanical ventilation hospitals are constantly expanding and trying to meet the overwhelming demand. Therefore, identifying COVID-19 characteristics, outcomes and associated factors among patients requiring mechanical ventilation is crucial for resource planning and proper management. This study is mainly aimed to assess the characteristic and outcome of COVID 19 cases admitted to ICU and mechanically ventilated patients. Objectives: The objective of this study is to assess characteristic, outcome and associated factors of COVID 19 cases admitted to ICU and mechanically ventilated at Eka Kotebe General Hospital. Study design: hospital based prospective cross sectional study design was used. Results: a total of 179 patients were included in this study and the 30 days mortality rate was 59.2 %. 77.1 % of the patients had comorbidities. Male gender, history of Diabetes, CKD and uses of vasopressor and laxatives were associated with 30 days patient mortality. Recommendation: We recommend that Male patients, patients diagnosed with Diabetes Miletus, CKD and who are receiving vasopressor therapy should be given a higher priority and carefully followed in the ICU to decrease the mortality rate.en-USCOVID 19,ICUThesis