Akalu, Luelayehu(Assistant Professor )Jima, Selam (B.Sc. M.Sc)Mamo, Temesgen2020-03-232023-11-052020-03-232023-11-052019-05http://etd.aau.edu.et/handle/123456789/21205Introduction: Spinal anesthesia is a type of regional anesthesia, has been practiced for obstetric anaesthesia since the beginning of the 20 th century.so it is easy to perform and reliable as well avoids the depressant effects of anesthetic drugs and has a potential to provide excellent operating conditions for caesarean section. Hypotension is a usual consequence of sympathetic motor and sensory block caused by spinal anesthesia for cesarean section. Objectives: The objective of the study is to determine the incidence and associated factors for hypotension after spinal anesthesia during cesarean section at Gandhi memorial hospital, Addis Ababa, Ethiopia. Method: Institutional based cross sectional study was conducted on 422 clients using structured questionnaire until the end of the operation. The study was conducted on cesarean section under spinal anesthesia from January, to April 30, 2019 at Gandhi memorial Hospital, Addis Ababa, Ethiopia. Systematic random sampling technique was used for selecting the sample. Both bivariate and multivariate logistic regression analysis were done for associated factors. Level of statistical significance was declared at p-value less than 0.05. Results: The incidence of hypotension among mothers who undergone cesarean section after spinal anesthesia was 64%. Neonate weight of 2.5-3.9kg AOR=3.440; 95% CI:( 1.441-8.211) and greater than 4kg AOR=4.957; 95%CI: (1.563-15.722) showed increased association with hypotension. A baseline systolic blood pressure less than 120mmHg AOR= 5.527; 95%CI: (2.695-11.336), and in the range of 120-130mmHg AOR=3.583; 95%CI: (1.980-6.485) was associated with hypotension. Sensory block height >T6 AOR= 2.272; 95%CI: (1.362-3.788) and the time interval between spinal induction and skin incision > 6minutes AOR=1.758;95%CI: (1.022-3.024) are also associated with hypotension after spinal anesthesia. Conclusion: The risk of hypotension is high in cesarean section after spinal anesthesia. The identified risk factors for spinal anesthesia induced hypotension are sensory height block, weight of the baby, time interval between spinal induction and skin incision, the baseline systolic blood pressure and experience of anesthetist.en-USHypotension, spinal anesthesia, cesarean section, Addis Ababa, EthiopiaThesis