Dr. Abdi FeyisaDr. Bethel BefekaduTsedale Teshome2023-12-092023-12-092023http://etd.aau.edu.et/handle/123456789/510An estimated 2.5 billion people depend on agriculture for their livelihood, and 1.3 billion people are employed by it. Livestock make up about 30% of the income from agriculture in poor nations like Ethiopia. Ethiopia has a significant quantity of livestock; however, the industry is characterized by low output since a variety of diseases are common. Therefore, the goal of this case study was to compile a clinical case report on the major disease of veterinary importance at Fisseha Gebreab memorial Veterinary Teaching hospital of CVMA, Bishoftu, Ethiopia from September 2022 to June 2023. Twenty cases were studied and compiled following the scientific case publishing format where abstract, introduction, case description, tentative diagnosis, laboratory diagnosis and result, treatment, and outcome of the disease were briefly recorded. The findings of each case were finally discussed concerning the findings in other literature and scientific publications. The twenty compiled case studies include ten cases on ruminants, two cases on equines, three cases on poultry, three cases on canines, and one case on pigs. Of a total of twenty cases, nine cases (47.6%) were caused by bacteria, six cases (28.6%) were caused by parasitic agents, four cases (19.05%) by viral particles, and one case (4.7%) were caused by a fungal pathogen. Therefore, clinical diagnosis complimented by laboratory examination is recommended to initiate effective treatment and control measures that safeguard the health and welfare of the treated animal and reduces the spread of infection to other animals or, in the case of zoonotic disease, to humans.encase studytreatment and outcomeCase descriptionThesis