Tsige, Yosief (PhD)Mulugeta, Tefera2018-07-192023-11-062018-07-192023-11-062011-06http://etd.aau.edu.et/handle/123456789/9387Background: Although it has been suspected from the early 1970s that there is a risk of impairment of cognitive function associated with type 2 diabetes mellitus, it is only more recently that interest has increased in research on possible mechanisms of this association and cognitive function of a patient with type 2 diabetes is not usually evaluated in routine clinical care. Aim: To assess the cognitive status of patients with type 2 diabetes and identify factors associated with it detected by MMSE. Methods: Institution based crossectional quantitative study carried out on 384 clients with type 2 diabetes mellitus who were selected by convenient sampling. The data was collected by interview using minimental state examination form. Data entry was done in Epi Info version 3.5.1 and then the data exported to SPSS version 16.0 for analysis purpose. Prior to actual data collection, ethical clearance was taken from Addis Ababa University; School of Medicine Department of Nursing and Midwifery and Tikur Anebessa Hospital. Result: A total of 384 type 2 diabetes mellitus outpatient respondents were participated in this study. The total MMSE score was 24.32 ± 3.510 points, with a range from 13 to 30. When the interpretation of this row score modified with educational level, 96(25%) respondents were cognitively impaired. Male respondents were found to be significantly, however; negatively associated with impaired cognitive status. Clients with less than grade 8 education were a highest increase in odds of poor cognition than higher education of their complements. Moreover, respondents having lower income were 2.6 times positively associated with impaired cognitive status than respondents with high income. Study subjects aged 41-50 and 50-60 were shown to have less cognitive impairment than aged 61 and above of their counterparts respectively. In addition, respondents who have been using insulin therapy were presented as impaired cognitive status as compared to those OHA users when analyzed with binary logistic regression. Conclusion and recommendation: Patients with type 2 diabetes should be regularly evaluated for their cognitive function, because duration and severity of disease could be associated with decline in cognition. The early implementation of mini-mental, which is a simple method of execution, can be done to detect early stages of cognitive impairment. Future studies will be important to better identify risk factors for cognitive dysfunction and lighten its relationship with diabetes.enPatientsType 2 diabetesThesis