Berihun, Assefa(Ph.DTessema, Meaza2021-08-042023-11-182021-08-042023-11-182020-11http://etd.aau.edu.et/handle/12345678/27587The major objective of this study was to examine the psychological problems of parents of children with cancer disease in Tekur Anbesa specialized referral hospital. The study was employed descriptive survey design with quantitative research method. The data were collected from 199 parents of children with cancer disease using simple random sampling technique. A standardized DAS scale was used to measure the psychological problems of study participants. To analyze the collected data both descriptive ((frequency, percentage, mean and standard deviation) and inferential statistics (Independent sample t-test and One-way ANOVA) was computed. The result from descriptive statistics showed that majority(57.29%) of study participants had mild, moderate, sever, and extremely sever state of depression and similarly more than half of study participants also reported mild, moderate, sever and extremely sever level of anxiety. With regard to stress; however, majority (64.82%) of study participants had a normal state of stress. The independent t-test also revealed that there was not a variation in psychological problems (depression, anxiety and stress) between male and female parents of children with cancer disease. The result from one way- ANOVA also showed that there is no statistically significant difference in depression, anxiety and stress among emerged, young and middle adult parents of children with cancer disease. With regard to educational status, the one way- ANOVA similarly showed that no significant difference in depression, anxiety and stress between non-educated and high-school completed, non-educated and diploma and above holders, primary school completed and high-school completed, primary school completed and diploma and above holders, high-school completed and diploma and above holder parents of children with cancer disease. However, one way ANOVA showed that non-educated parents had higher psychological problems (I.e. depression and anxiety) than primary school completed parents. Based on the finding of the study the researcher; therefore, recommended for Tikur Anbesa specialized referral hospital to improve and make it strong their guidance and counseling system.enThesis