Deribe Leul (BSc)Abebaw Nigusie2018-11-282023-11-062018-11-282023-11-062018-06http://etd.aau.edu.et/handle/123456789/14616Introduction: According to the World Health Organization definition, puerperal sepsis is a genital tract infection occurring within the rupture of placental membranes or labor until 42nd days of post-partum period. This disease is characterized by two or more of such symptoms as pelvic pain, fever (i.e., oral temperature of 38.5°C or higher on any occasion), abnormal vaginal discharge and delay in the reduction of the uterus size. Objectives: Assessments of the prevalence and associated factors of puerperal sepsis among post natal women in Dessie referral hospital, Ethiopia, 2017/2018. Materials and Methods: A retrospective cross-section study design was conducted among postnatal women in Dessie referral hospital.The study samples were selected by systematic sampling procedure that full fill the inclusion criteria to be selected during the study period.EPI data version3.1 was applied to enter the data.SPSS version 20 was used for analysis of theresult. Bi variable and multi variable regression was carried out to determine the association between the outcome variable and independent variables. RESULT: the result of the finding showed that from 422 samples 24(5.7%) were developed puerperal sepsis during child birth and post-partum period. this study showed that the age of respondents ranged from 15 to 46 years, with a mean of 26.73 with SD 5.12 years. and also from the total numbers of child births, 55.5 % were primi gravid. Vaginal examination. (OR=7.22, 95% CI, 2.22-23), body temperature ((OR=4.01, 95%CI, 1.09-14.7).mode of delivery (OR=4.77, 95%CI, 1.38-16.47) and duration of membrane rupture (OR=6.22, 95% CI, 1.93-20.0) were the most significant association with development of puerperal sepsis during child birth and post –partum period. CONCLUSION: generally the prevalence of Puerparal sepsis was 5.7 % .to reduce this problem Management staffs and health profession staffs should also consider integrating hygiene education and Puerperal sepsis awareness was important to prevent and control puerperal sepsis for women during child birth and post-partum period.en-USpuerperal sepsis, prevalence, associated factors, Dessie referral hospital.Thesis