Dr.Taye, Girma(MSc, Ph.D. Associate Professor)Ayele, Wondimu(MSc, Ph.D. Fellow)Duressa, Belay Fanta2021-05-162023-11-052021-05-162023-11-052021-02http://etd.aau.edu.et/handle/123456789/26437Background The district health information system plays a critical role in supporting evidence-based decision-making for all system pillars. However, health workers do not fully utilize district health information for decision-making. Hence, to ensure the effective and efficient utilization of health information, periodic assessment becomes very crucial. The aim of the study was, therefore, to assess the utilization of district health information for decision making and its associated factors among case team heads in selected public health institutions of Addis Ababa City Administration, Ethiopia from February to April 2020. Method: A cross-section study design was conducted using a quantitative approach. A pretested & standard PRISM tool was administered to collect quantitative data from 240 case team heads in 23 selected health institutions. Data were entered by Epi-data and were cleaned and analyzed by SPSS version 23.0. Descriptive statistics were used to summarize key findings. Logistic regression was used to assess factors associated with outcome variables and findings were reported using crud and adjusted odds ratio and corresponding 95% confidence interval. Result: A total of 234 case team heads participated in the study with a response rate of 97%. Out of the total, 55.1% were females. About 164(70.1%) of them have less than 5 years‟ work experience and only 90(38.5%) participants attended training on DHIS2 software; Over all, the proportion of utilization of district health information among case team heads in health institutions was about 41.5%( 95%CI: 35.09-47.81). Among other factors ICT infrastructure (AOR 5.03, 95% CI 4.02-9.67), financial support (AOR 5.68, 95% CI 9.84-15.39), access of training (AOR 3.64 95% CI 4.75-7.28), supportive supervision (AOR 2.50, 95% CI 1.23-3.16), were significantly associated utilization of DHIS2 data. Conclusion and recommendation: Generally, this study revealed that poor utilization of district health information among the case team heads in health institutions. Inadequate ICT infrastructure, poor supportive supervision, shortage of financial support, training gaps of the users, were reduces the utilization of district health information s. It needs major improvement to avail ICT infrastructure; computer, internet connectivity, coordinated supervision and fill training gaps to enhance the confidence of the DHIS2 users.en-USHealth information systems, utilization of DHIS, DHIS2 software.Thesis