Assegid, Meselech ( MPH, Assistance professor)Seifu, Abiy (MPH,Assistant Professor)Awol, Munir(MD, Assistant Professor of Clinical Oncology)Gebrehiwot, Yirgu(MD, MSc, Associate Professor of Gynecologic Oncology)Fitiwe, Wintana2021-04-082023-11-052021-04-082023-11-052020-12http://etd.aau.edu.et/handle/123456789/26001Abstract Back ground:Globally,cervical cancer is the fourth most common cancer in women with most of the deaths occurring in developing countries, particularly in low- and middle income countries. In Ethiopia, evidences suggested that many women seek treatment in the advanced stage of the disease which complicates management and intervention of the disease.Data on levels and factors associated to late stage of diagnosis are limited. Objective:To assess the magnitude and factors associated withlate stage at diagnosis of cervical canceramongcervical cancer patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia from July 22 to October 30, 2020. Methods: A facility based cross sectional study was conducted among cervical cancer patients referred to Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Data was collected using a structured interviewer administered questionnaire and patient’s medical records were reviewed to extract relevant information.Every consecutive new case of cervical cancer patient who came during data collection period were enrolled in the study.Data was codedand entered in to Epidata 4.64 andexported to Stata 14 for cleaning, recoding and analysis. Descriptive statistics were computed to describe the characteristics of study participants. Those variables with p-value<0.05 at 95%CI in the multivariable binary logistic regression were considered as having a statically significant association with the outcome variable,late stage at diagnosis.Stage at diagnosis was determined using the International Federation of Gynecology and Obstetrics (FIGO) staging system. Result:A total of 392 women with confirmed cervical cancer were enrolled. The mean age of the patients was 58 ± 10 years, majority 257(65.56%) were married, more than half (56.63%)came from rural area and 229 (58.42 %) had no formal education. About 53.8% of patients were diagnosed with late stage disease. The odds of late stage diagnosis of cervical cancer was more than two times higher AOR=2.38 [95%CI: 1.03, 5.11] among those patients who had poor knowledge, about four times higher AOR= 3.41 [95%CI: 1.69, 6.88] among patients who were residing in rural areas, two times higher AOR=2.03[95%CI: 1.03, 3.99] among patients who had shared their symptom late with someone. Conclusion: This study identified that poor knowledge of cervical cancer, women residing in rural areas and patients who shared their symptom late with someone were more likely to be diagnosed at late stage of cervical cancer.Providing health education for women on early detection methods and raising public knowledge in more comprehendible way is needed for early diagnosis of cervical cancer.en-USCervical cancer, late stage diagnosis, knowledgeThesis