Dr.Kebede, Tedla(MD, Associate Professor)Dr.Zemenfes, Abel(MD, Associate Professor)Mengesha, Wodajo2022-02-282023-11-052022-02-282023-11-052021-12http://etd.aau.edu.et/handle/123456789/30391Background: Diabetic retinopathy and diabetic kidney disease are microvascular complications of diabetes mellitus. Patients with diabetic retinopathy are prone to develop diabetic kidney disease. However, there is limited evidence on the relationship between diabetic retinopathy stages and diabetic kidney disease severity. Objective: To identify the relationship between patterns of diabetic retinopathy and diabetic kidney disease Methods: A hospital based cross-sectional study was conducted at diabetes clinic of TASH, Ethiopia from June 2021 to July 2021. Structured questionnaire, patients’ charts and/or electronic medical records were used to collect data among 101 diabetic patients with diabetic retinopathy aged 18 years and above. Data were cleaned, coded and entered into IBM SPSS version 26 software for analysis. Descriptive and logistic regression analyses were used and P-value < 0.05 was used as statistically significant. Results: The mean (±SD) age of the participants was 52.9 (±11.8) years. Majority (94.1%) of our diabetic retinopathy patients had nonproliferative retinopathy and 70.3% of diabetic retinopathy patients had concomitant diabetic kidney disease. In multivariable logistic regression analyses, diabetic retinopathy severity (severe nonproliferative diabetic retinopathy to proliferative diabetic retinopathy vs. mild to moderate nonproliferative diabetic retinopathy) [AOR= 3.97; 95% CI: 1.01 - 15.62], T2DM [AOR= 3.74; 95% CI: 1.29 - 10.75], presence of CVD [AOR= 3.18; 95% CI: 1.05- 9.59] were the independent predictors of diabetic kidney disease. Conclusions: In this study, diabetic retinopathy severity was strongly associated with diabetic kidney disease. Therefore, evaluation of diabetic retinopathy severity at the time of retinal screening is recommended. Budget grant: Addis Ababa University (AAU), College of Health Sciences, School of Medicineen-USDiabetic retinopathy, Diabetic kidney disease, TASH, EthiopiaThesis