w/yohannes, Misrak (PhD)Tilahun, Abere2018-06-132023-11-052018-06-132023-11-052017-06http://etd.aau.edu.et/handle/123456789/738Background: Nausea and vomiting during regional anesthesia for cesarean section are very common and unpleasant events. Can cause significant distress to the patient and interfere with the surgical procedure. Identifying the factors of nausea and or vomiting during cesarean section in specific context can help to reduce negative consequence of nausea and or vomiting during cesarean section delivery. Objective: The objective of this study was to assess Magnitude of nausea and or vomiting and its associated factors among mothers taking spinal anesthesia for cesarean section at Gandhi memorial hospital, Addis Ababa, Ethiopia Methods: Institutional based cross sectional study was conducted on 140 obstetric mothers who gave birth under cesarean section with spinal anesthesia at Gandhi memorial hospital from March to May 2017. Systematic random sampling technique was used to select study participants from operation order during arrival. Necessary information was obtained from each mother and medications, producers and vital signs were recorded. Bivariate and multivariate regression analyses were used to identify risk factor for the development of nausea and or vomiting. P value blow 0.05 was considered statistically significant Result: The overall magnitude of nausea and or vomiting was 54.3 %, Factors associated with postoperative nausea and or vomiting were mothers who did not took metoclopramide prophylaxis (AOR=2.958, 95% CI: (1.084-8.072), long duration of uterus exteriorization (AOR=1.387, CI=1.109-1.734) and intraoperative shivering (AOR=6.133, CI=2.17-17.332) showed strong odds of develop nausea and or vomiting than their counterpart. Conclusion and recommendation: Nausea and or vomiting among mothers gave birth under cesarean section with spinal anesthesia is significantly high. This study found that mothers who did not took metoclopramide prophylaxis, long duration of uterus exteriorization and intraoperative shivering were factors associated with nausea and or vomiting. We recommended that metoclopramide prophylaxis should be administered before surgeryen-USMemorial HospitalThesis