Asfaw, Nigist (PhD)G/Heiwot, Kibrom2018-06-202023-11-092018-06-202023-11-092006-07http://etd.aau.edu.et/handle/12345678/2191Laggera tomentosa is a perennial fragrant bushy herb endemic plant of Ethiopia. Chemical investigation on the ethanol extract of the leaves resulted in the isolation of one sesquiterpene and two flavones namely, 3-(3’- acetoxy-2’- hydroxy-2’-methyl butyryl)- cuauhtemone(LTE-3), 3’, 5, 6-trihydroxy -3, 4’, 7- Trimethoxyflavone (LTE-5), 3’, 4’, 5, 7-tetrahydroxy -3, 6- dimethoxyflavone (LTE-6). Of these LTE-3 and LTE-6 were not reported before to the best of our knowledge. The structures of the isolated compounds were established by spectroscopic techniques and chemical correlation.enLaggera tomentosaThesis