Gebreyesus, Tarekegn (PhD)Barbe, Paulos2018-06-212023-11-092018-06-212023-11-091991-09http://etd.aau.edu.et/handle/12345678/2779The Sponge Xestospongia sp. from the Red Sea has been ehemically investigated. The chloroform soluble portion of the ethanolic extract of the sponge yielded P-Sl, a minor metabolite which could not be identified, and P-46. P-46 was obtained from the chloroform soluble portion of the ethanolic extract by repeated VLC and CC on silica gel; recrystallization yielded colorless rod-shaped crystals (0.002%) P-46 was identified as petrosin on the basis of spectral studies including IR, ElMS, 13C Nl>!R, HMQC, one and zn_1H NMR as well as by comparison of its spectral and physical data with those reported for petros in. The newly generated HMQC data confirmed the previously assigned structure of petros in unequivocallyenXestospongia spThesis