Ali, AhmedBulti Jira, Fikre2018-08-062023-11-052018-08-062023-11-052016-05http://etd.aau.edu.et/handle/123456789/11065Title: Measles Outbreak Investigation in Sayo Nole District, West Wollega Zone, Oromia Region, Ethiopia-February, 2015 Back ground: Measles is a highly contagious viral disease causing public health problem in developing countries despite the presence of an effective vaccine. Vaccine strategies targeted children. The Oromia Regional Health Bureau received reports of a measles outbreak from Sayo Nole Woreda of west Wollega Zone on 10/2/2015. We investigated to confirm the outbreak, identify risk factors, and implement control measures. Methods: We defined a suspected measles case as any person with fever, rash, cough, and coryza or a person suspected of measles by a clinician. From January 16 to 25, 2015 .we investigated all cases in the affected District using line lists and questionnaires and compared cases with controls. Epi info version 7.1 was used for analysis of the findings. Results: During the study period we identified 68 suspected cases and with no death. The median age of the cases was 10 years (range 6 months to 55 years), and 95% of the cases were greater than 5 years old. The vaccination rate among cases was 55%. We compared 60 cases to 120 controls and found that families size greater than five (odds ratio (OR) =9.4, 95% confidence interval (CI): (4.5-19.3) and lack of information about the mode of transmission of measles (OR= 16, 95%CI: 7.4-36.2) were risk factors. However, being vaccinated for measles (OR= 0.46, 95% CI: 0.2-0.9) was a protective factor. Conclusions: Measles outbreak has occurred due to low vaccination coverage and lack of awareness on how to be prevented from it. Educating community on mode of transmission, strengthening expanded immunization coverage and conducting active surveillance should be enhanced to cease the outbreak in the District. Key words: measles, outbreak, Investigation, Sayo Nole, 2015enmeasles, outbreak, Investigation, Sayo Nole, 2015Thesis