Yemane, Sisay (PhD)Belay, Meseret2019-09-042023-11-052019-09-042023-11-052018-06http://etd.aau.edu.et/handle/123456789/18991The overriding purpose of this study is to assess the over all association between depression, Anxiety, stress and academic achievement among undergraduate medical students. The study was conducted in saint Paul hospital millennium medical college in Gulele sub city Addis Ababa. Stratified random sampling methods were used to used to select the respondents of the study among 719 students enrolled in saint Paul hospital millennium medical college during 2005- 2010 academic year. The quantitative data was gathered by the help of self administer validate questionnaire and was analyzed by the help descriptive statistics that consist o weighted inferential by Pearson chi-square test and one way analyses of ANOVA. As finding of study Chisquare test analyses of the association between prevalence of DAS and academic achievements’ of medical students found that there was a statistically significant association between levels of anxiety and students’ academic achievement at less than 0.05 significant level (X2=20.02,p<0.05). However, statistically significant associations were not observed between level of depression and stress with academic achievements’ of medical students in the study site during the survey period. The overall prevalence of depression, anxiety and stress among the respondents were 47.5%, 61.2% and 36.6%, respectively using the standard DAS 42 questionnaire. These figures are too high by any standards. So, to mitigate the problem, the stakeholders including health professionals would better give awareness about the overall problems accompanied by depression, anxiety and stress. Since this study found that statistically significant association between levels of anxiety and students’ academic achievement using chisquare test analyses, stake holders shall be in a better commitment position to seriously advice their students about how anxiety affects their academic performance. Monitoring and evaluation strategy shall also be introduce Key Words ; Depression, Anxiety, Stress, Medical StudentsenDepressionAnxietyStressMedical StudentsThesis