Epidemiology

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Browsing Epidemiology by Subject "Gastro-intestinal cancer, Quality of life, TASH, Ethiopia"

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    Assessment of quality of life among adult gastrointestinal cancer patients in Tikur Anbessa specialized hospital, Ethiopia.
    (Addis Abeba University, 2020-06) Gebregiorgis, Helen Gebrelibanos; Taye, Girma(Ph.D., Ass.Prof.)
    Background- Non-communicable diseases are now accountable for the majority of global deaths and cancer is anticipated to rank as the leading cause of death and one of the threats to escalating life expectancy in every country of the world in the 21st century. Cancer is recognized to reduce the quality of life, thus has a negative impact not only on physiological symptoms but also on the psychological functioning of the individual. The objective of the study was to assess the quality of life among adult Gastro-Intestinal Cancer patients in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia, 2019. Method- Institution based cross-sectional study was done in Tikur Anbessa specialized hospital from February to April 2019 on adult Gastrointestinal (GI) cancer patients. All consecutive GI cancer patients were included, a total of 250 participants. The validated Amharic version questioner of the European organization for research and treatment of cancer core 30 and diseasespecific questioner for each of GI cancers was used.The dependent variable Global health status (QOL)was dichotomized with a cutoff point above and below 50 for interpretation. Association between each variable with QOL was examined using binary logistic regression. Variables with pvalueof<0.2on bi-variate were candidate for multivariable logistic regression analysis. Result-A total of 250 study participants were in the study period, among them 159 were colorectal cancer,40 esophageal cancer, 39 gastric cancer, and 12 hepatocellular cancer. The response rate was 95.7%. The mean ±SD score of QOL of CRC, esophageal cancer, gastric cancer and HCC was 52.8±21.02,37.2±17.29,47.4±20.9 and 30.5±18.57 respectively. Sex (AOR=6.3 95%CI=1.8322.12),occupational status (AOR=0.06 95%CI=0.01-0.3), clinical-stage (AOR=4.98 95%CI=1.51-16.4), physical functioning (AOR=1.04 95% CI=1.01-1.06), social functioning(AOR=1.02 95%CI=1.01-1.06), financial difficulty (AOR=0.975 95%CI=0.959-0.99), stoma presence (AOR=7.98 95%CI=1.51-16.45), blood and mucus in stool (AOR=0.93 95%CI=0.900.96)had an association with QOL for CRC patients. Conclusion and recommendation-Quality of life of Gastrointestinal cancer patients were very poor. The focus should have to be given for their respective symptom scales by responsible stakeholders.