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Ethiopian Field Epidemiology Training Program (EFETP) Compiled Body of Works in Field Epidemiology

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dc.contributor.advisor Aynalem, Getahun(PhD)
dc.contributor.author Hiluf, Tigabu
dc.date.accessioned 2018-07-17T07:48:45Z
dc.date.available 2018-07-17T07:48:45Z
dc.date.issued 2014-04
dc.identifier.uri http://localhost:80/xmlui/handle/123456789/8965
dc.description.abstract Introduction: Tsegedea district is found in western Tigray region composed of 123,641 populations and 25 kebelles. The health facility coverage is 100 %( 5) for health centers and 93 %( 23) for health posts. Measles is an acute, highly contagious viral disease caused by measles virus.. As more countries immunize more children, measles deaths have been reduced by 71 per cent—from an estimated 548,000 in 2000 to 158,000 in 2011.However, according to the official report, an outbreak of measles is occurring throughout the regions of Ethiopia. Among these regions, Tigray region has reported 6 outbreaks of measles from, 2011-2013. We received 4 clinically suspected measles cases from 2 kebelles of the district from 6-10/2/2014. We investigated this cluster to confirm its etiology, describe its magnitude, identify potential risk factors and make recommendations. Methods: We investigated measles outbreak from 6-24/2/2014 in Tsegedea district by a casecontrol study. We recruited 20cases and 40controls by simple random sampling having a structured questionnaire. We entered the data to Epi-Info, version 7.6.1 and exported to SPSS, version 16 for analysis. We have computed the BMI, overcrowdings, vaccine efficacy (1-OR)*100 and herd immunity (from 2012-2014). Results: we detected a prevalence of 0.23/1000(29) with 100 %( 7) IgM positive in Tsegede district. It was higher in males 51.8 %( 15) than females 48.2 %( 14).The median age was 9years (8month-30years) with ASAR of 0.277/1000(1) for <1 years and 0.22/1000(15) in >=15 years age. Majority of the cases were in Alemgenet Kebelle( 2.19/1000(10)) compared to the other 6 kebelles that ranges 0.1/1000-1.1/1000.We computed a herd immunity of 73.1% and a vaccine efficacy of 94.1% for one dose vaccinated Vs non-vaccinated .55% of the cases enrolled to the study were underweight .The vaccination of 1 dose and >=2 dose were a protective factor for developing measles infection(i.e for 1 dose, AOR =0.059,95%CI(0.008-0.44), P-value=0.0060 ,for >=2,AOR=.061,95%CI(0.004-0.9) ,P-value=0.045). Overcrowding was also highly associated with the occurrence of measles outbreak (AOR= 8.42, 95%CI (1.76-40.1), P-value= 0.007). 2 Conclusion: compared to the national measles vaccination policy, the herd immunity was low with higher vaccine efficacy. The vaccination status and overcrowding had a strong relationship with measles infection separately. The measles outbreak was a propagative that lied majority of the cases in >= 15 years age and specific areas of the district. So, that, a selective vaccination campaign, improvements on housing condition and nutritional status of the community should be implemented. en_US
dc.language.iso en en_US
dc.publisher Addis Ababa University en_US
dc.subject Epidemiology en_US
dc.title Ethiopian Field Epidemiology Training Program (EFETP) Compiled Body of Works in Field Epidemiology en_US
dc.type Thesis en_US

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