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Antimicrobial Activity of Solvent-Extracts of Cucumis Ficifolius and Zehneria Scabra on Some Test Microorganisms

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dc.contributor.advisor Mekonnen, Yalemtsehay (Professor)
dc.contributor.author Gelana, Tegenu
dc.date.accessioned 2018-07-11T11:28:56Z
dc.date.available 2018-07-11T11:28:56Z
dc.date.issued 2011-08
dc.identifier.uri http://localhost:80/xmlui/handle/123456789/8013
dc.description.abstract The crude chloroform, ethyl acetate, acetone, methanol and ethanol extract of the leaves of Cucumis ficifolius and Zehneria scabra were tested against in vitro antibacterial activity of five human pathogenic bacteria using disc diffusion method and agar dilution method for Minimum Inhibitory Concentration (MIC). Pseudomonas aeruginosa and Shigella boydii were susceptible test organism for the ethyl acetate and acetone extracts of the leaves of C. ficifolius with inhibition zones of 14±0.577mm, 12±0.577mm and an MIC of 0.781mg/ml, 3.125mg/ml respectively, but Escherichia coli and Salmonella typhi were the most resistant bacteria to all extracts of the leaves of this plant species with no inhibition zones. Staphylococcus aureus and E. coli were found to be the most susceptible bacteria for the ethyl acetate and acetone extracts of the leaves of Z. scabra with inhibition zones of 22.6±0.33mm, 14±0.577mm and MIC of 0.781mg/ml, 1.56mg/ml respectively. However S. typhi was the most resistant to all extracts of the leaves of this plant with no inhibition zone. The acetone extracts of C. ficifolius and the ethyl acetate extracts of Z. scabra were most potent but the chloroform extracts of both medicinal plants were ineffective against all bacterial and fungal test organisms. C. ficifolius and Z. scabra didn’t show any inhibitory activity against Botrytis and Fusarium. It can be concluded that C. ficifolius and Z. scabra had shown antibacterial activity having potential for further study to serve as source of antibacterial agents. Key words and phrases: Antibacterial activity, antifungal activity, minimum inhibitory concentration, Cucumis ficifolius, Zehneria scabra. en_US
dc.language.iso en en_US
dc.publisher Addis Ababa University en_US
dc.subject Antibacterial activity en_US
dc.subject antifungal activity en_US
dc.subject minimum inhibitory concentration en_US
dc.subject Cucumis ficifolius en_US
dc.subject Zehneria scabra en_US
dc.title Antimicrobial Activity of Solvent-Extracts of Cucumis Ficifolius and Zehneria Scabra on Some Test Microorganisms en_US
dc.type Thesis en_US


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