Environmentally friendly way of handling industrial effluents is the most important concept for industries direct and/or indirect contribution of a country’s sustainable development. In 12 order to achieve such goals biological processes play the major role. This study was also initiated to evaluate the treatment performance of a laboratory scale anaerobic/anoxic/aerobic (A/A/A) bioprocess system for the removal of phosphorous from brewery wastewater. For this purpose the treatment plant was fed with raw brewery wastewater collected from St. George Beer Factory at three different organic loading rates (OLR) (0.5, 0.75 and 1 kg COD/m3 day). The set-up was inoculated with sludge biomass obtained from the oxidation ponds of Meta Abo Beer Factory. And the treatment performance of the set-up was evaluated using the parameters PO4-3, TN, NH4+-N, NO3--N, COD, BOD5 and pH concentrations. The results showed that brewery wastewater used in this study was medium to high strength wastewater with COD, BOD5, PO4-3, TN,NH4+-N and NO3- -N values ranging from 1860- 3880, 484-636, 31.9-121.7, 44-78, 12.2-54.2 and 13-36 in mg/l, respectively. The set-up used was able to achieve 80.0, 78.9 and 66.8 % removal of PO4-3, 69.7, 67.6 and 54.0 % removal of TN, 95.67, 93.8 and 87.9 % removal of NH4+-N and 51.1, 46.5 and 44.3 % removal of NO3- -N at 0.5, 0.75 and 1 kg COD/m3 day of OLRs, respectively. In addition to these the bioprocess gave 97.2, 96.5 and 95.6 % removal efficiencies for COD and 92.8, 91.7 and 89.3 % removal efficiencies for BOD5 at OLRs of 0.5, 0.75 and 1 kg COD/m3 day, respectively. The laboratory scale treatment plant performed well and gave maximum removal efficiencies at organic loading rate of 0.5 kg COD/m3day where TP (PO4-3), TN, NH4+-N, NO3--N, COD and BOD5 concentrations decreased from 54.9, 71, 39, 36, 2240 and 636 mg/l to 11.0, 21.5, 1.7, 17.6, 62 and 46 mg/l, respectively. There was a correspondence observed between the maximum removal efficiency of the set-up and the increase in biomass concentration of the system. The results of this study indicated the possibility of handling brewery wastewater biologically in an environmentally friendly manner using A/A/A biological nutrient removal configuration.