• Five-year Trend Analysis of Tuberculosis Burden in Bahir Dar, Northwest Ethiopia, 2015 - 2019 

  Mekonnen, Dagmawi Mengesha (Addis Abeba University, 2021-07)

  Background: Tuberculosis (TB) remains a major cause of morbidity and mortality in Ethiopia despite the increased availability of effective treatments. Trend analysis of issues and priorities affecting TB programs across ...
• Five-year survival status of women diagnosed with cervical cancer and treatment impact at Tikur Anbessa hospital, Addis Ababa, Ethiopia; a retrospective cohort study 

  Mose, Olyad (Addis Abeba University, 2021-06)

  Background: Worldwide, cancer of the cervix is one of the most common causes of cancer mortality among women, with about 288,000 deaths each year. While it is the second leading cause of cancer mortality among adult ...
• Efficacy and safety of vaccine trials conducted in Africa: a systematic review and Meta-analysis. 

  Tesfai, Sara (Addis Abeba University, 2021)

  Background: vaccine preventable diseases have been of global concern. Vaccines are the best way for prevention. Studies are showing that there is disparity in efficacy of vaccines, in industrialized and in low-middle ...
• Assessment of Prevalence and Associated Factors of Polypharmacy among Elderly Patients Admitted to Federal Police Referral Hospital, Addis Ababa, Ethiopia 

  Geleta, Melka (Addis Abeba University, 2021-08)

  Background: Polypharmacy is one of the major concerns in the healthcare sector as it has a strong association with increased treatment costs, morbidity and adverse drug reactions (ADR). Elderly patients are prone to these ...
• Treatment Outcome of Drug-resistant Tuberculosis and Associated Factors at St.peter Specialized Hospital Addis Ababa, Ethiopia. 

  Abebe, Mekdelawit (Addis Abeba University, 2021-08)

  INTRODUCTION:Drug Resistant Tuberculosis is defined as tuberculosis that does not respond to antituberculosis agent. Data on the outcome of MDR/RR-TB and associated factors is highly needed to evaluate the efficiencies ...
• Digital health interventions for clinical care and treatment of tuberculosis and HIV: Capacity and readiness assessment of healthcare facilities in Addis Ababa, Ethiopia 

  Adere, Emnet Getachew (Addis Abeba University, 2021-06)

  Background: Digital Health Interventions (DHIs) such as electronic health (eHealth) and mobile health (mHealth) are emerging as promising technologies to advance clinical care and treatment. However, many of these ...
• Assessment of capacity for conducting drug trials in Ethiopia: a cross-sectional situation analysis 

  Amano, Aliyi (Addis Abeba University, 2021-07)

  Abstract Background: Several development organizations have argued that clinical trials (CTs) in LMICs are crucial for advancing public health and development. In order to ensure that clinical trials facilities (CTFs) ...
• A systematic Review and Meta-analysis of Antimicrobial Prescriptions in East Africa 

  Joan, Acam (Addis Abeba University, 2021-06)

  Background: Antimicrobial resistance is one of the major global health problems that has been worsened due to poor antibiotic stewardship by health workers and improper use of antimicrobial by the patients among other ...
• Self sampling HPV testing as cervical cancer screening approach among women living in low-middle-income -countries: Systematic review and Meta-analysis. 

  Amanuel, Hanna (Addis Abeba University, 2021)

  Background: More than 85% of cervical cancer deaths occur in low-middle-income countries, and 90% of the mortality burden is primarily attributed to low coverage of cervical cancer screening. Self-sampling HPV could ...
• System and site readiness for conducting active surveillance of adverse Events following Immunization in Addis Ababa, Ethiopia. 

  Dagnachew, Eden (Addis Abeba University, 2021-06)

  Background: Vaccine pharmacovigilance (PV) aims to detect, assess, comprehend, communicate and manage adverse events following immunization (AEFI). To help distinguish vaccine related AEFIs from coincidental occurrences, ...
• Impact of COVID-19 on tuberculosis and HIV care and treatment services in Addis Ababa, Ethiopia. 

  Haile, Dagmawi Chilot (Addis Abeba University, 2021-06)

  Background:Coronavirus disease 2019 (COVID-19) pandemic has infected 173,674,509 people globally resulting in 3,744,408 deaths as of 09 June 2021.Ethiopia is categorized under COVID19 epidemic phase III (advancing ...
• Comparison of efficacy and safety of dihydroartemisinin- piperaquine versus artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in African children: Systematic review and metaanalysis of randomized control trials 

  Assefa, Dawit Getachew (Addis Abeba University, 2021-06)

  Background: Emergence of Plasmodium falciparum resistance to artemisinin and its derivatives poses a threat to global effort in controlling malaria. Resistance has already emerged to most antimalarial drugs in common ...
• Association of Maternal Dietary Pattern and Neural Tube Defects; A Case-control Study in Addis Ababa, Ethiopia 

  Mohammedsanni, Afrah (Addis Abeba University, 2020-07)

  Background: Neural Tube Defects (NTDs) are significant public health problems with complex etiology. Maternal nutrition is one of the environmental factors to contribute to the etiology of NTDs. This study aims to assess ...
• Survival of Patients with Tuberculosis in Retreatment Programme with Guardian Administered Streptomycin in Malawi 

  Mboma, Fides Christina (Addis Abeba University, 2021-07)

  Background: Current ambulatory approaches for delivering treatment to patients with tuberculosis in Malawi have significant operational delivery challenges. This led to a clinical trial aimed at establishing if guardian ...
• Challenges and strategies for recruitment and retention of participants in clinical trials in Ethiopia: a qualitative study 

  Wagaw, Lealem Minwuyelet (Addis Abeba University, 2020-11)

  Introduction: Clinical trial is an extensive and demanding process, which takes approximately 10 to 15 years. Clinical trials require the active engagement of human subjects. Recruitment and retention of participants are ...
• Challenges and prospects of the regional bioequivalence center initiative in Ethiopia: a qualitative study. 

  Melesse, Yajeb (Addis Abeba University, 2020-10)

  Background: Evaluation of the interchangeability of multi-source generic drug products or bioequivalence study has become a crucial activity since the share of generic medicines in healthcare has enormously grown over ...
• Eastern Africa Countries Need and Readiness for Implementation of Harmonized Clinical Trials Regulation and National Ethics Review System: A Qualitative Study 

  Ejamo, Assefa (Addis Abeba University, 2020-11)

  Background: Medical products are regulated from premarket clinical trials to post marketing surveillance and phase IV clinical trials. Research organizations have responsibilities to conduct clinical trials subject to ...
• Investigating researchers’ perceptions and experiences in conducting clinical trials toward zoonotic diseases in Ethiopia 

  Adugna, Senait Belay (Addis Abeba University, 2020-06)

  Background: The emergence and resurgence of zoonotic diseases have continued to be a major threat to global health and the economy. Developing countries are particularly vulnerable due to agricultural expansions and ...
• Bacteriophage to overcome Nosocomial infections associated with multidrug-resistant bacterial pathogens: a systematic review and meta-analysis 

  Benson, Ngolobe (Addis Abeba University, 2020-06)

  Background : Antibiotic-resistant pathogens constitute an important and growing threat to public health. The emergence of multidrug-resistant organisms in nosocomial infections is being highly associated with frequent ...
• Regulatory System Opportunities and Barriers for Conducting Clinical Trials in Ethiopia: A Descriptive Qualitative Study 

  Maru, Mehiret (Addis Abeba University, 2020-06)

  Introduction: A clinical trial is a research method used to provide evidence on the safety and effectiveness of interventions for specific medical conditions. In contrary to the disease burden, most of the clinical trials ...

View more