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Browsing Pharmacology by Issue Date

Browsing Pharmacology by Issue Date

Now showing items 1-20 of 114

Evaluation of Anti-Inflammatory and Wound Healing Activities of the 80% Methanol Fruit Extracts Of Dovyalis Abyssinica A. Rich. in Mice

Abdissa, Hailu (Addis Ababa University, 2011-10)

Dovyalis abyssinica locally known as “Koshim” is traditionally used to treat conditions such as hemorrhoids, ulcers and swelling of the throat. The toothbrush sticks are also reported to be used for oral hygiene. There ...
Evaluation of Renoprotective Effects of Euclea Divinorum Hierns Against Gentamicininduced Nephrotoxicity in Rats

Feyissa, Tadiwos (Addis Ababa University, 2011-10)

Despite their nephrotoxicity and ototoxicity, aminoglycoside antibiotics (such as gentamicin and amikacin) are still considered to be important agents against lifethreatening infections owing to their bactericidal efficacy, ...
Synthesis, Antimalarial and Antileishmanial Evaluation of Some Quinazoline Derivatives

Simegniew, Yihenew (Addis Ababa University, 2012-01)

Malaria and leishmaniasis are neglected tropical parasitic diseases affecting billons of people around the globe. Owing to their promising antimalarial and antileishmanial activities, seven novel 2-(substitutedstyryl)-3- ...
Renal Effects of Crude Khat (Catha Edulis F.) Extract when Administered alone and Concomitantly with Gentamicin in Rats

Shewamene, Zewdneh (Addis Ababa University, 2012-08)

Khat use has been reported to produce significant acute and chronic toxic effects including oxidative damage of cellular macromolecules such as DNA, lipids and proteins contributing to the development of several pathologies, ...
Evaluation of in Vitro and in Vivo Antitrypanosomal Activity of Aqueous and Methanol Leaf Extracts of Clutia Abyssinica (Euphorbiaceae) and Verbascum Sinaiticum (Scrophulariaceae) Against Trypanosoma Congolense Field Isolate

Mergia, Ermias (Addis Ababa University, 2014-01)

Aqueous and methanol leaf extracts of C. abyssinica and V. sinaiticum were investigated for the presence of secondary metabolites, their in vitro and in vivo activity against Trypanosoma congolence, the main causative ...
In Vitro and In Vivo Anti-trypanosomal Activity of Dichloromethane and Methanol Crude Leaf Extracts of Dovyalis abyssinica (Flacourtiaceae) against Trypanosoma congolense Field Isolate

Tadesse, Belay (Addis Ababa University, 2014-01)

African Trypanosomosis is a neglected tropical disease of medical and veterinary importance. Parasite control relies on the use of few drugs whose resistance and unacceptable toxicities urged the investigation of new ...
Evaluations of the Effect of Subchronic Administration of Crude Khat Extract (Catha Edulis F.) on Learning and Memory in Mice

Mohammed, Faiz (Addis Ababa University, 2014-01)

Learning may be defined as the ability to alter behavior based on experience. If there is no learning, there can be no memory later. Memory is the ability of an individual to record sensory stimuli; events, information, ...
In Vivo Antimalarial Activity of Solvent Fractions of the Leaf of Justicia Schimperiana Hochst. Ex Nees (Acanthaceae) Against Plasmodium Berghei in Mice

Abdela, Jemal (Addis Ababa University, 2014-02)

In spite of tremendous reduction in malaria-associated morbidity and mortality achieved during the last decade, malaria still remains a major global public health problem accounting for about 219 million infections and ...
Evaluation of In Vivo Antihypertensive and Ex Vivo V asodepressor Activities of the Seed Extract of Calpurnia aurea (Ait.) Benth.subsp. aurea (Fabaceae)

Getiye, Yohannes (Addis Ababa University, 2014-03)

Being the most important modifiable risk factor for stroke, renal, vascular and heart diseases; hypertension is still one of the leading causes of disability, morbidity and mortality among the populace worldwide. Consequently, ...
Evaluation of in vivo Anti-diarrheal Activity of 80%Methanolic Extract of the Leaves of Croton macrostachys Hochst. (Euphorbiaceae) in Rats

Bussa, Zebenay (Addis Ababa University, 2014-03)

Diarrhea is a common cause of death in developing countries. It is also one of the primary causes of morbidity and mortality on a global scale, leading to 1 billion disease episodes and 1.8 million deaths each year, among ...
In-vivo Anti-inflammatory Effect of the Roots of Indigofera spicata Forssk in Mice

Seid, Jibril (Addis Ababa University, 2014-04)

The search for new anti-inflammatory agents from the huge array of medicinal plant resources is intensifying because currently available anti-inflammatory drugs pose a major problem including induction of gastric or ...
Evaluation of Analgesic and Anti-Inflammatory Activities of Solvent Fractions of the Leaves of Moringa Stenopetala Bak.F. In Swiss Albino Mice

Tamrat, Yohannes (Addis Ababa University, 2014-05)

Many people still experience pain and inflammation regardless of the available drugs for treatments. In addition, the available drugs have many side effects, which necessitated a quest for new drugs from several sources ...
Evaluation of Analgesic and Anti -inflammatory Activity of Moringa stenopetala Bak.(Moringaceae) in Mice

Geremew, Helen (Addis Ababa University, 2014-06)

Moringa stenopetala Bak F.is commonly used in folk medicine as a single drug remedy to treat various aliments like; hypertension, headache, stomach disorders, asthma, diabetes and malaria. However, the use of the herb ...
Evaluation of the Antidepressant-like Activity of the Crude Extract and Solvent Fractions of Rosa abyssinica Lindley (Rosaceae) Using Rodent Models of Depression

Fekadu, Netsanet (Addis Ababa University, 2014-06)

Depression is a disorder often manifested with symptoms at the psychological, behavioral and physiological levels. Herbal medicine holds a valuable place in the treatment of depression. It is also a reasonable alternative ...
Evaluation of the anti-diarrheal activity of the solvent fractions of Croton macrostachyus Hocsht. ex Del. (Euphorbiaceae) leaves in mice

Degu, Amsalu (Addis Ababa University, 2014-10)

Traditional healers in Ethiopia use a wide range of medicinal plants with antidiarrheal properties. Among these, Croton macrostachyus is one such plant claimed to have an antidiarrheal activity in Ethiopian folklore medicine. ...
Assessment of Antidiabetic Medication Adherence and Its Effect on Glycemic Control in Ambulatory Patients with Type 2 Diabetes at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia

Tsehay, Tessema (Addis Ababa University, 2014-12)

Poor adherence to treatment of chronic diseases is a worldwide problem of striking magnitude. Adherence to long-term therapy for chronic illnesses in developed countries averages 50%. In developing countries, the rates ...
Evaluation of the Antidiarrheal Activity of 80% Methanol Extract of the Aerial Parts of Ajuga remota Benth in Mice

Yacob, Teshager (Addis Ababa University, 2014-12)

In the Ethiopian traditional medicine, the aerial parts of Ajuga remota Benth ( Local name, Armagusa) is used in the treatment of diarrhea. Since this claim has not been investigated scientifically, this study was ...
Assessment of Drug Related Problems in Medical Wards of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia

Biset, Mohammed (Addis Ababa University, 2015-01)

Drug related problems are common in hospitalized patients. Ten to thirty percent of hospital admissions are thought to be directly related to drug related problems. Drug related problems may lead to reduced quality of ...
Factors Associated with Underutilization of Inhalation Corticosteroids among Asthmatic Patients Attending Tikur Anbessa Specialized Hospital

Ayele, Yohanes (Addis Ababa University, 2015-01)

Inhalation Corticosteroids (ICS) is a cornerstone medicine for preventive therapy of persistence asthma. However, underutilization of ICS is common and little is known about factors contributing to this underutilization. ...
Assessment of Adherence and Treatment Outcome among Epileptic Patients on Follow-up at Amanuel Specialized Mental Hospital

Gedamu, Melak (Addis Ababa University, 2015-02)

Anti-epileptic drugs (AEDs) are the primary therapeutic modes for epileptic patients and have been demonstrated to control seizure, which decreases morbidity and mortality associated with epilepsy. There is a paucity of ...

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