Background: Accidents occurring in most industries in Ethiopia are a source of worry to everyone. Most employers fail to use adequate health and safety measures in place at their workplace to safeguard not only the employees and management but also clients and other stakeholders who might have some kind of interest in the company or institution.(3) The metal & engineering corporation is a labor intensive task. As these workers perform repetitive tasks throughout the work day, they may face several work related problems. Objective: The main objective of this study was to assess the level of knowledge, their attitudes & practices among the workers towards safety measures to prevent the above mentioned problems. Methods: A descriptive cross-sectional study was conducted in METEC in March 2014. A total of 422 study populations were randomly selected from the eight industries according to their worker number proportion. The data was collected using the structured interview questionnaires. The questionnaire was pre-tested for their accuracy and validation prior to the actual study and the necessary adjustments were done accordingly. The data were entered after being encoded and analyzed using SPSS. Results: The mean (standard deviation) age of the respondents was 33.526 (1.04) of the respondents recognized at least one safety sign. 84 (19.9%) respondents got information from health facility and 79.16% of the respondents had “High knowledge” of used PPE and 13.27% showed “Moderate knowledge” and 7.58% had ”Low knowledge. The distribution of attitudes on using PPE is 76.5% of respondents had “Positive attitude”. 6.13% of them had “Neutral attitude” While 17.37% of respondents had “Negative attitude”. Among the respondents, 89.6% had ever been using at least one kind of PPE, while 10.4% had never used any PPE. Conclusion and recommendation: The workers have high knowledge level compared to other studies. Health and safety recommendations have positive effects on both knowledge levels and safe practices. Health and safety training has positive effects on safe practice but did not impact knowledge. Health and safety recommendation should be given to the workers. Safety signs should posted at a reasonable work sites. Keywords: Safety knowledge, attitude, practice and PPE