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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/16938
Title: Assessment of Renal Stone Composition and Associated Risk Factors Among Patients Attending Urology Department of St. Paul’s Hospital Millennium Medical College and Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia
???metadata.dc.contributor.*???: Dr. Mistire Wolde (PhD)
Dr. Mulat Taye (Assistant professor)
Ms. Hiwot Abebe (MPH)
Ms. Sameria Solomon (Assistant professor)
Mr. Atsbeha G/Egziabher (MSc)
Mr. Abebe Edao (MSc)
Hamelmal Kibe
Keywords: Renal calculi, Urolithiasis, Nephrolithiasis, Stone composition, Ethiopia
Issue Date: Aug-2017
Publisher: AAU 2017
Abstract: Background: Urolithiasis or renal stone is a global problem whose incidence is reported to be on the rise across the world. It is a common and a major cause of morbidity worldwide including Ethiopia. Therefore, this study was aimed to increase understanding of the prevalence and risk factors of renal stone in Addis Ababa, Ethiopia. Objective: To evaluate renal stones chemical composition and associated risk factors among patients attending at urology department of St. Paul Hospital Millennium Medical College and Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Method: Across sectional study was conducted at the department of urology, TASH and SPHMMC from January to April 2017. Seventy three adult patients with renal stones who were eligible for inclusion included in this study. Blood, urine and renal stone samples were collected at SPHMMC and TASH. Stones were chemically analyzed for about ten types of renal stone composition. The collected data was entered into excel, cleaned and analyzed using SPSS version 20. Result: During the study period a total of 73 study participants attended urology department at TASH and SPHMMC were included, out of these 52 (71.2) were Males. Male to female ratio was 2.5:1. The age of study subjects having stone was ranging from 20 to 71years. The mean age of the study subjects was 39 (SD 12.5) years. Majority (34.2 %) of the participants were in the age group of 35-44 years. Majority of the calculi were composed of calcium oxalate, phosphate, magnesium, magnesium-phosphate and ammonia. In most cases mixed form of calculi (91.8%) were observed .There was an association between phosphate composition with male sex, urinary pH and occupation with ammonia. Conclusion and recommendation: Stones containing calcium oxalate were predominant across the age groups and in both sexes. Further study on larger sample size is recommended.
Description: A THESIS SUBMITTED TO THE DEPARTMENT OF MEDICAL LABORATORY SCIENCES, SCHOOL OF ALLIED HEALTH SCIENCES, COLLEGE OF HEALTH SCIENCES, ADDIS ABABA UNIVERSITY IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTERS OF SCIENCE IN CLINICAL LABORATORY SCIENCE (CLINICAL CHEMISTRY SPECIALTY TRACK.
URI: http://hdl.handle.net/123456789/16938
Appears in Collections:Thesis - Medical Laboratory

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