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Title: Chemical Constituent of Euclea Schimperi
???metadata.dc.contributor.*???: Dr. Ermias Dagne
Tesfai, Zerom
Issue Date: Jun-1988
Publisher: Addis Ababa University
Abstract: There are two indegineous Euclea species in Ethiopia of a total of nearly 20 species of Euclea in the world all of which are restricted to tropical and subtropical Africa, Euclea schimperii (family Ebenaceae), known in Amharic as Dedeho, is used in Ethiopia traditional medicine for the treatment of gonorrheae. The extract obtained from the root bark afforded seven naphthoquinones and two triterpenes, Five of the naphthoquinones are known compounds, these being 7-methyljuglone (N-l), neodiospyrin (N-2), 2-methylnaphthazarin (N-3), mamegakinone (N-4), and isodiospyrin (N-7), The other two naphthoquinones have not yet been structurally elucidated. The two triterpenes are lupool (T-l) and unidentified triterpene (T-3)', The extract from the stem-bark of E, schimperi yielded isodiospyrin (N-7), lupeol (T-l), and another uncharacterized triterpene (T-2), From previous phytochemical reports it appears that out of the known naphthoquinones isolated neodiospyrin (N-2) and 2-methylnaphthozarin (N-3) have not been re- ported before from any part of the plant. Furthermore, the occurrence of neodiospyrin (N-2) from the genus Euclea is reported here for the first time.
Description: A Thesis Presented to School of Graduate Studies Addis Ababa University in Partial Fulfillment of the Requirements for the Degree Master of Science in Chemistry
Appears in Collections:Thesis - Chemistry

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