|Title:||Distribution of Drug Resistance among Enterococci, Salmonella and Escherchia Colt 0157:117 Isolates from Poultry and Cattle Faeces|
|???metadata.dc.contributor.*???:||Prof. Mogessie Ashenafi|
|Keywords:||Antibiotic Resistance;Enterococci;Escherichia Col/ 0157:117;MDR;Salmonella|
|Publisher:||Addis Ababa University|
|Abstract:||Surveillance of the prevalence of zonootic bacteria and resistant commensals in food animals is necessary to control the spread of the pathogens and resistant commensal bacteria to humans through contaminated animal food products and to the environment via their faecal material. This study was designed to see the prevalence of antibiotic resistance in enterococci from poultry and cattle; to asses the prevalence of E.coll 0157 117 from cattle, and that of Salmonella from cattle and poultry. Two hundred eighty clonal swabs collected from poultry were examined for the presence of Salmonella and enterococci and the isolates were tested for their resistance to an array of 8 and 11 different antibiotics, respectively. Similarly, 450 fresh faecal samples collected from cattle were examined for the presence of E. colt 0157 H7, Salmonella and enterococci. The Salmonella and enterococci isolates from cattle were tested for their resistance to an array of 8 and 9 different antibiotics, respectively. Entercoccus faecium was the most dominant species in both poultry and cattle (49.6% and 34/64), followed by Enterococcus durans (26.9% and 21164). The prevalence of Salmonella in poultry and cattle was 15.4% and 1.8%, respectively. None of the cattle faecal samples was positive for Escherichia col/ 0157:H7. Resistance to the antibiotics tested was seen in all species from poultry. All E. faecalls Isolates showed susceptibility to amikacin. There was no significant difference among farms and species in their percentage of resistant isolates to the different antibiotics, except difference among farms in percentage mean resistant isolate for penicillin G and vancomycin (at 0=0.05). Vancomycin resistance was observed in 44% of enterococcal Isolates from poultry in the four farms and in 17% isolated from cattle. Multiple drug resistance (MDR) was observed in 78.2% and 90.6% enterocccal isolates from poultry and cattle, respectively. Entercoccal isolates from cattle showed resistance with varying percentage to all antibiotics tested, except amikacin. Among the Salmonella isolates 16 from poultry and 1 from cattle showed MDR. The presence of MDR isolates In the commensal and pathogenic microbes is a serious public heath concern. The government and concerned bodies should focus and work more in the area.|
|Description:||A Thesis Presented to the School of Graduate Studies of the Addis Ababa University in Partial Fulfillment of Requirements for the Degree of Masters of Science in Biology (Applied Microbiology)|
|Appears in Collections:||Thesis- Microbial, Cellular and Molecular Biology|
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