Due to the growth in the network usage, there is huge traffic pressure to server clusters in the datacenters. To manage incoming traffic, operators choose a load balancing technology to assign the incoming traffic to server clusters. However, this classical load balancing technology has complexity and challenge in scalability, flexibility and manageability. But, the emerging software defined networking having application, control and infrastructure layers offers an advantage of low cost, scalable, programmable and easy management to server clusters load balancing activity by abstracting the low level functionality of the network. This study evaluates the performance of round robin, weighted round robin and least load server cluster load balancing algorithms using software defined networking open Flow model by providing ethio telecom’s enterprise shop customers relation Management system users’ data as input in order to answer a research question of which load balancing algorithms is better in terms of network performance parameters such as response time, transaction per second, throughput in SDN platform. Simulation has been used as a methodology to evaluate server load balancing algorithms using Open Flow model by creating a virtual environment with oracle virtual box. In addition, mininet simulation tool has used to create the network topology and POX controller used in the control layer of the open Flow model to do the performance evaluation of the load balancing algorithms. The simulation result shows that round robin algorithm is better than weighted round robin and least load server load balancing algorithms interms of response time (sec), transaction rate (trans/sec), throughput (MB/sec).