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Title: Serum Immunoglobulin Levels in Healthy Ethiopian School Children
???metadata.dc.contributor.*???: Dr. Ayele Belehu
Dr. Abebe Harege
Gebremariam, Zinabu
Issue Date: Jun-1982
Publisher: Addis Ababa University
Abstract: Serum concentrations of immunoglobulins IgG, IgA and IgM in 258 healthy Ethiopian school children and 82 healthy adults resid¬ing in Addis Abeba were measured by the radial immunodiffusion technique# The results are presented as geometric mean values in mg/100 ml and as percent of the adult mean values. A statis¬tical analysis showed that the IgG and IgA concentrations at ages 8 and 7 respectively were lower than the adult values. The inference drawn from these results is that the IgG and IgA levels do not reach the adult level until after the age of 8 and 7 respectively. In contrast the IgM level v/as found to reach the adult level before the age of 7, No truly significant differences were observed in immunoglobulin levels which could be attributed to sex, intestinal parasitic infection or socioeconomic status. The mean values for IgG and IgM obtained from this study were found to be higher than the reference values being used in the country at the moment. It is thus suggested that mean immunoglobulin concentration values obtained from this study be used as reference values until further study is made and more refined reference values are set.
Description: A Thesis Presented to the School of Graduate Studies Addis Ababa University In partial fulfilment of the requirements for the degree of Master of Science in Biology
Appears in Collections:Thesis - Biology

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