|Title:||Staphylococcus Aureus from Surgical, Departments of Hospitals in Addis Ababa: Staff Carriage Rates, Environmental Contamination and Antibiograms|
|???metadata.dc.contributor.*???:||Dr. Messele Gedebou|
|Publisher:||Addis Ababa University|
|Abstract:||Six hundred strains of Staphylococcus aureus were isolated from the Black Lion Teaching Hospital Surgical Department environment (353), from the nose,' wrist and arm skin of surgical staff of six selected hospitals in Addis Ababa (161), and a non-hospital population (86). Out of 454 surgical staff examined, 139 (30.6%) were nasal carriers and 22 (51%) of 43 nasal carriers also. carried the organism on their skin. Carrier rates among different categories of surgical staff varied; the highest rate was among surgeons (56%) t the non-hospital population comprised 328 students, and 21.6% of them were nasal carriers. Of 53 non-hospital nasal carriers 15 (27%) were found to carry the organism on their wrist skin. The carrier rate of the non-hospital population was significantly lower (P<0f01) than that of the hospital population. The rate was higher in males than in females in hospitals, but not in the non-hospital population. The environment of operating rooms and surgical wards of Black Lion Teaching Hospital was highly contaminated with Staph, aureus, Over 75% of air samples and 37% of dust samples were positive, •The non-hospital isolates were much more sensitive to antibiotics than the hospital isolates. Over 96% of non-hospital isolates were sensitive to nine antibiotics, but only $7% and 74% were sensitive to penicillin and tetra¬cycline respectively. About 90% of all isolates were sen¬sitive to clindamycin, cephalothin, gentamicin, kanamycin and trimethoprim-sulfamethoxazole, and none was resistant to vancomycin* The majority of hospital staphylococci, 87% of surgical staff isolates and 60% of environmental isolates were resistant to penicillin, and over 60% of both types of isolates resistant to tetracycline. About 94% and 88% of hospital and non-hospital staphy¬lococci, respectively, were resistant to at least one an¬tibiotic. Multiple resistance among non-hospital staphy¬lococci was remarkably lower (2.3%) than that of hospital isolates (over 37%) Different types of antiprograms were detected: 66 among environmental, among surgical staff, And 6 among non-hospital isolates. These varied between resistance to one and to nine antibiotics. Combined resis¬tance to penicillin and tetracycline was the most frequent pattern. The findings were compared with other reports from Ethiopia and elsewhere* Based on the present study and other similar recent reports-from Addis Ababa, the need for strict antibiotic policy, continued surveillance, assignment of infection officers and maintenance of clean-liness of the hospital environment have been stressed.|
|Description:||A Thesis Pres ented to the School of Graduate Studies Addis Ababa University In Partial Fulfillment of the Requirements for the Degree Master of Science in Biology|
|Appears in Collections:||Thesis - Biology|
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