School of Pharmacy: Recent submissions

Now showing items 1-20 of 397

Ex-Vivo Vasodilatory Activity and Possible Mechanisms of Action of Distillated Seed Extract From Lupinus Albus L. (“Gibto Arekei”) in Isolated Guinea Pig Thoracic Aorta

Likey, Yoseph (Addis Abeba University, 2021-10)

Hypertension is a major health problem globally necessitating exploration for new preventive and therapeutic tools. The community in North Western Ethiopia uses a local alcoholic beverage from Lupinus albus L. seed called ...
Assessment of Drug Therapy Problems and Contributing Factors among Adults Admitted to Tirunesh Beijing General Hospital, Addis Ababa, Ethiopia

Ababiya, Tsegaye (Addis Abeba univerisity, 2021-11)

The philosophy of pharmaceutical care (PC) is the sum of responsibilities of the pharmacist to meet all of the patient’s drug-therapy needs through direct patient care and cooperation with other facets of the health care. ...
In Vivo Anti-malarial Activities of the Solvent Fractions of the Roots of Euphorbia Abyssinica J.F.Gmel (Euphorbiaceae) against Plasmodium Berghei Infection in Mice

Fikadu, Muluemebet (Addis Abeba univerisity, 2022-05)

Despite all the advances in the health care system, malaria remains a devastating problem in subSaharan Africa. Moreover, resistance to the existing pharmacological agents is the major factor overrating the issue. Therefore, ...
Assessement of Sanitary Conditions of Food Service Establishments and Food Safety Knowledge, Attitude and Practices among Food Handlers in Burayu Town

Bekele, Mamo (Addis Abeba University, 2021-11)

Background: Poor knowledge, attitude and practices of hygiene can contribute to the outbreaks of food borne illness. Most foods could be affected by food borne pathogens mainly due to poor hygienic conditions and inappropriate ...
Assessment of Prerequisite Programs for Implementation of Hazard Analysis and Critical Control Point and Associated Factors among Hotels and Restaurants of Dukem and Bishoftu Towns of Ethiopia

Yadesa, Dano (Addis Abeba University, 2022-04)

Background: Prerequisite programs like GHP and GMP support the basic environmental and operating conditions which are important for the production of safe and wholesome food in the food establishments. Set of procedures ...
Anticonvulsant Activity of Soxhlet Leaf Extracts of Ajuga Integrifolia Buch.Ham ex D.Don (Lamiaceae) in Mice

Desalegn, Tesfaye (Addis Ababa University, 2021-11)

Epilepsy is one of the most common chronic neurological conditions that affect 70 million people in different parts of the world. The leaves of Ajuga integrifolia Buch.ham ex D Don have been used as anti-convulsant remedy ...
In Vitro Anti-leishmanial Activities of 80% Methanol Extract of Brucea Antidysenterica J.F. Mill Seeds and its Solvent Fractions

Ketema, Tasisa (Addis Ababa University, 2022-04)

Leishmaniasis is a neglected tropical disease threatening lives of about 350 million people , globally. However, the currently available treatment options are limited and have drawbacks including variable efficacy, ...
Determination of Antibiotic Residues (Tetracycline, Oxytetracycline, and Penicillin G) in Beef for Public Consumption at Dukem and Bishoftu Towns, Central Ethiopia

Uma, Gudeta (Addis Ababa University, 2022-03)

Penicillins and tetracyclines class antibiotics are among the most commonly used in livestock farm. Indiscriminate use of these substances in Cattle may leave unsafe level of residues in edible tissues that could cause ...
Anti-Malarial Drug and Mosquito Net Use Pattern in Pawe Special Woreda: A Community Based Survey

Mussa, Seid (Addis Ababa University, 2009-06)
Eradication of Helicobacter Pylori with Standard Triple Therapy and its Clinical Implications

Gebeyehu, Endalew (Addis Ababa University, 2021-09)

Background: Helicobacter pylori eradication based on standard triple therapy (STT) has been accepted to curb risks associated with H. pylori infection, commonly chronic gastritis and peptic ulcer disease. However, rate of ...
Cost as a Barrier to Access: Availability, Affordability and Identifying Component Cost of Essential Medicines

Nuru, Mohammedsied (Addis Ababa University, 2009-06)
Assessing Knowledge, Attitude, Prevention on Practice and Regulatory Body Practices of Food Adulteration on Selected Food Items among Bahir Dar City Dwellers

Fenta, Misganaw (Addis Ababa University, 2021-12)

Background: Food adulteration is an addition of another substance to a food item to increase the quantity which may result in the loss of actual quality of the food item. This practice critically diminishes the nutritional ...
Synthesis, Characterization and Evaluation of Nanocellulose- based Nanogels from Local Sources for Sustained Drug Delivery

Gabriel, Tesfaye(PhD) (Addis Ababa University, 2022-03)

Polysaccharides possess great potential advantages in the development of drug delivery vehicles due to their biocompatibility, biodegradability, and amenability for modifications. Cellulose, a well-known ubiquitous ...
Antidepressant-like Activity of Solvent Fractions of the Root Bark of Carissa spinarum Linn. (Apocynaceae) in Rodents

Saif, Hana (Addis Ababa University, 2022-03)

Depression is a chronic and recurrent psychiatric disorder affecting mental and physical health. Traditional medicines have been used for decades in the treatment of depression due to resistance development, side effects, ...
Characterization of the Short-Term Effects of Prenatal Asphyxia and Screening of Some Ethiopian Medicinal Plants for the Probable Preventive Role in Rats.

Engidawork, Epbrem (Addis Ababa University, 1997-04)

Perinatal asphyxia results from failure of normal respiratory gas exchange during or soon after labor and it remains an important cause of permanent neurological deficit in surviving infants. The most common features are ...
Evaluation of the Anti Peptic Ulcer Activity of the Leaf Extract of Plantago Lanceolata in Rodents.

Melese, Endale (Addis Ababa University, 2010-02)

The lesion of peptic ulcer disease (PUD) is a disrflption in the mucosal layer of the stomach or duodenum. An ulcer is di stinguished from erosion by its penetration through the muscularis mucosa or the muscular coating ...
Microencapsulation of Citronella Oil for Mosquito Repellent Application Formulation, Optimization, and in Vitro Permeation Studies

Solomon, Bezayit (Addis Ababa University, 2009-09)

Citronella oi l (CO), has been reported to possess a mosquito repellent action. However, its application in topical preparations is limited by its rapid volatility. The objectives of this study were to confirm its activity ...
Development and Validation of a Predictive Model for Severe Hematological Toxicity in Adult Colorectal Cancer Patients Taking Chemotherapy at Tikur Anbessa Specialized Hospital

Ayenew, Wondim (Addis Ababa University, 2021-10)

Background: Hematological toxicities are common in colorectal cancer patients taking chemotherapy. The development of a valid predictive model would go a long way in preventing for such toxicities. Objectives: To ...
Anticonvulsant Effect of Pterlobium stellatum (Leaves), Moringa stenopetala (Root) And Clutia abyssinica (Leaves) Traditionally Used for Treatment of Epilepsy in Ethiopia Using Mice Model

Sahile Salile, Samson (PhD) (Addis Ababa University, 2021-06)

Background :Epilepsy is the third leading contributor to the global burden of disease for neurological disorders and affects 65 million people worldwide. Although the current antiepileptic drugs achieve symptomatic ...
Preparation, Characterization of Cellulose Acetate from Cotton Linter andEvaluation as a Sustained Release Excipient in Tablet Formulations

Teshome, Melaku (Addis Ababa University, 2021-11)

Cotton linter (CL) is a by-product of the garment industry that is good raw material for cellulose preparation. The aim of this study was to extract and characterize native cellulose and cellulose acetate (CA) from CL ...

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