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Title: Visceral leishmaniasis in Bira Abo, a kebele in Addis Zemen: Sero-epidemological and Leishmanin Skin Test Survey
Authors: Seleshi, Kebede
Advisors: Prof. Asrat Hailu,DMIP,AAU
Copyright: 2007
Date Added: 23-Apr-2008
Publisher: Addis Ababa University
Abstract: Abstract Visceral leishmaniasis is a serious public health problem of global importance, with a total of 200 million people at risk, an estimated 500 000 symptomatic new cases each year worldwide. The aim of this study was to determine the prevalence and exposure of Visceral leishmaniasis in Bira Abo kebele, one of the localities in Addis Zemen (Northern Ethiopia) in June 2006.Sero-epidemological and Leishmanin skin test survey of VL was carried out. A total of 1280 subjects comprising 709 males and 571 females and 30 previously treated VL patients were included in the study. After clinical screening, 1280 sera were tested by Direct Agglutination Test (DAT) to determine prevalence of leishmanial antibody. The rate varied from 2.9% to 14.1% among the different localities. The overall DAT positivity was 8.4%.Leishmanin Skin Test (LST) was used to determine exposure, with rate varied from 6.2% to 28.6% and with 12.3% over all prevalence. The difference in leishmanin positivity by study sites and sero prevalence by sex were all statistically significant (x2=67.59; P <0.01 and x2 =14.76; P<0.05 respectively). Out of sero positive individuals 7 were young children (<5 years), who had no history of travel out of Bira Abo, suggesting that transmission occurred in the study site. Hence, there is a need to implement a sound control program. positive for M. bovis. The results indicated that M. tuberculosis is the causative species for tuberculous lymphadenitis in Dera.
Description: A thesis submitted to the School of Graduate Studies of Addis Ababa University in partial fulfillment of the requirements for the Degree of Masters of Science in Medical Parasitology
URI: http://hdl.handle.net/123456789/914
Appears in:Thesis - Medical Parasitology

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