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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/333

Title: Voltammetric study of paracetamole using glassy carbon electrode
Authors: Abrha, Berhe
Advisors: Prof. Theodros Solomon
Copyright: 2007
Date Added: 11-Dec-2007
Publisher: Addis Ababa University
Abstract: This paper describes the use of electro analytical techniques, cyclic voltammetry (CV), square wave voltammetry (SWV), and differential pulse voltammetry (DPV) in the study of the electrochemical behavior of paracetamol in aqueous media and at the glassy carbon electrode. The electrochemical reaction was found to be irreversible, involving the transfer of two electrons. Aqueous phosphate buffer pH 7 was used as solvent and supporting electrolyte. An optimization of instrumental parameters was performed for the differential pulse and square wave voltammetric techniques. Differential pulse amplitude, pulse repeat time, and scan rate chosen for differential pulse voltammetry were 30 mV, 0.5 sec, and 5 mv/s respectively. Similarly for square wave voltammetry, the amplitude, frequency, and step potential chosen were 25 mV, 25 Hz, and 5 mV respectively. Finally the interference study of tablet was studied at aqueous phosphate buffer of pH 7.0.
Description: A Graduate project presented to the School of Graduate Studies Addis Ababa University in partial fulfillment of the requirement for the degree of Master of Science in Chemistry.
URI: http://hdl.handle.net/123456789/333
Appears in:Thesis - Chemistry

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