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|Title: ||Assessment of Adherence among Children on Antiretroviral Therapy in Addis Ababa|
|Authors: ||Woinshet, Melese|
|Advisors: ||Dr. Alemayehu worku (PHD)|
|Copyright: ||Jun-2008 |
|Date Added: ||11-May-2012 |
|Abstract: ||Introduction: The advent of potent antiretroviral therapy (ART) in 1996 led to a
revolution in the care of patients with HIV/AIDS in the developed world. However, the
efficacy of antiretroviral therapy (ARV) in suppressing viral replication and delaying the
progress of the acquired immunodeficiency syndrome (AIDS) is related to optimal
Objective: the main objective of this study was to assess antiretroviral (ART) adherence
among children in Addis Ababa.
Methodology: A hospital based cross-sectional study was conducted from Oct 2007-Jun
2008 in Addis Ababa. Data was collected by using a pretested structured questionnaire by
trained health care providers from 346 caregivers of children. This study was
supplemented by indepth interview with primary caregivers and health care providers. A
simple random sampling method was used to select hospitals and study subjects were
taken consecutively. Adherence to antiretroviral therapy in the previous seven days of the
interview was measured by self-report. Patients who reported an intake of more than 95%
of the prescribed medication were considered to be adherent. Bivariate and multivariate
logistic regressions were done to assess factors associated with adherence.
Result: A total of 273(78.9%) females and 73 (21.1%) male caregivers were interviewed.
The age of care givers ranged from 18 years to 78 years; the mean and the median age of
the primary care givers were 36 ±10.43 and 35, respectively and 178 (51.4%) females
and 168 (48.6%) male children were participants of the study through their care givers.
The mean and median ages of the children were 8.27±3.22 and 8 years. The overall
adherence in the pervious seven days was found to be 93.4%. Except age of the children
and occupational status of care givers, other variables were not found to be significantly
associated with adherence at P<0.05.
Conclusion and Recommendation: The magnitude of adherence in the health institution
is promising and encouraging the service delivery system as well as health professionals
is important to make it sustainable in turn to achieve a better treatment outcome and
prevent treatment failure.|
|Appears in:||Thesis - Public Health|
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