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Title: Assessment of Adherence among Children on Antiretroviral Therapy in Addis Ababa
Authors: Woinshet, Melese
Advisors: Dr. Alemayehu worku (PHD)
Copyright: Jun-2008
Date Added: 11-May-2012
Publisher: AAU
Abstract: Introduction: The advent of potent antiretroviral therapy (ART) in 1996 led to a revolution in the care of patients with HIV/AIDS in the developed world. However, the efficacy of antiretroviral therapy (ARV) in suppressing viral replication and delaying the progress of the acquired immunodeficiency syndrome (AIDS) is related to optimal adherence. Objective: the main objective of this study was to assess antiretroviral (ART) adherence among children in Addis Ababa. Methodology: A hospital based cross-sectional study was conducted from Oct 2007-Jun 2008 in Addis Ababa. Data was collected by using a pretested structured questionnaire by trained health care providers from 346 caregivers of children. This study was supplemented by indepth interview with primary caregivers and health care providers. A simple random sampling method was used to select hospitals and study subjects were taken consecutively. Adherence to antiretroviral therapy in the previous seven days of the interview was measured by self-report. Patients who reported an intake of more than 95% of the prescribed medication were considered to be adherent. Bivariate and multivariate logistic regressions were done to assess factors associated with adherence. Result: A total of 273(78.9%) females and 73 (21.1%) male caregivers were interviewed. The age of care givers ranged from 18 years to 78 years; the mean and the median age of the primary care givers were 36 ±10.43 and 35, respectively and 178 (51.4%) females and 168 (48.6%) male children were participants of the study through their care givers. The mean and median ages of the children were 8.27±3.22 and 8 years. The overall adherence in the pervious seven days was found to be 93.4%. Except age of the children and occupational status of care givers, other variables were not found to be significantly associated with adherence at P<0.05. Conclusion and Recommendation: The magnitude of adherence in the health institution is promising and encouraging the service delivery system as well as health professionals is important to make it sustainable in turn to achieve a better treatment outcome and prevent treatment failure.
URI: http://hdl.handle.net/123456789/3009
Appears in:Thesis - Public Health

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