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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/2578

Title: AEROBIC BACTERIA IN POST-SURGICAL WOUND INFECTION AND PATTERN OF THEIR ANTIBIOTIC SUSCEPTIBILITY IN HAWASSA TEACHING AND REFERRAL HOSPITAL, SOUTHERN ETHIOPIA
Authors: LOPISO, DESSALEGN TIRORE
Advisors: SOLOMON GEBRE-SELASSIE (MD, M.Sc)
ATO TECHALEW SHIMELIS (B.Sc, M.Sc)
ATO ENDALE TADESSE (B.Sc, M.Sc)
Keywords: susceptibility
post-surgical wound
Aerobic bacteria
Copyright: May-2011
Date Added: 4-May-2012
Publisher: AAU
Abstract: Background: Post-operative wound infections have been found to pose a major problem in the field of surgery for a long time. Advances in control of infections have not completely eradicated this problem because of development of drug resistance. This condition is serious in developing countries where irrational prescription of antimicrobial agents is common. Objective: To determine the distribution of common aerobic bacteria in post-surgical wound infected patients and their antimicrobial susceptibility patterns. Materials and Methods: This cross sectional study was carried out in a total of 194 patients with post surgical wound infections at Hawassa Teaching and Referral Hospital, from November 2010 to March 2011. Physicians collected data on socio-demography and clinical profiles using designed formats. Moreover, pus swabs were collected, processed and cultured using the standard bacteriological methods. Isolated organisms were tested for pattern of antimicrobial susceptibility using the standard disk diffusion method. The data were entered in to a computer and analyzed using SPSS Version-16 software. Results: The prevalence of aerobic bacteria was 71.1%, and majority of the isolates (59.3 %) were Gram-negative organisms. The most frequently isolated aerobic bacteria was S. aureus (37.3%), followed by E .coli (25.4%) and Klebsiella species (13.6%). All bacterial isolates were resistant to at least one antibiotic, and 86.4 % were resistant to more than one antibiotic (multiple drug resistance). Conclusion: Single and multiple drug resistance to the commonly used antibiotics in the study area was found to be very high leaving clinicians with a very few choices of drugs for the treatment of post surgical wound infected patients. Therefore, it is critical that use of antimicrobial agents with in hospitals, public healthcare providers as well as private ones should be reviewed and further studies to find out the overall resistance patterns and their possible causes and associated factors in the region at large need to be carried out.
URI: http://hdl.handle.net/123456789/2578
Appears in:Thesis - Medical Microbiology

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