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Addis Ababa University Libraries Electronic Thesis and Dissertations: AAU-ETD! >
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Thesis - Medical Microbiology >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/2578
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| Title: | AEROBIC BACTERIA IN POST-SURGICAL WOUND INFECTION AND PATTERN OF THEIR ANTIBIOTIC SUSCEPTIBILITY IN HAWASSA TEACHING AND REFERRAL HOSPITAL, SOUTHERN ETHIOPIA |
| Authors: | LOPISO, DESSALEGN TIRORE |
| Advisors: | SOLOMON GEBRE-SELASSIE (MD, M.Sc)
ATO TECHALEW SHIMELIS (B.Sc, M.Sc)
ATO ENDALE TADESSE (B.Sc, M.Sc) |
| Keywords: | susceptibility
post-surgical wound
Aerobic bacteria |
| Copyright: | May-2011 |
| Date Added: | 4-May-2012 |
| Publisher: | AAU |
| Abstract: | Background: Post-operative wound infections have been found to pose a major problem in the
field of surgery for a long time. Advances in control of infections have not completely eradicated
this problem because of development of drug resistance. This condition is serious in developing
countries where irrational prescription of antimicrobial agents is common.
Objective: To determine the distribution of common aerobic bacteria in post-surgical wound
infected patients and their antimicrobial susceptibility patterns.
Materials and Methods: This cross sectional study was carried out in a total of 194 patients with
post surgical wound infections at Hawassa Teaching and Referral Hospital, from November 2010
to March 2011. Physicians collected data on socio-demography and clinical profiles using
designed formats. Moreover, pus swabs were collected, processed and cultured using the standard
bacteriological methods. Isolated organisms were tested for pattern of antimicrobial susceptibility
using the standard disk diffusion method. The data were entered in to a computer and analyzed
using SPSS Version-16 software.
Results: The prevalence of aerobic bacteria was 71.1%, and majority of the isolates (59.3 %) were
Gram-negative organisms. The most frequently isolated aerobic bacteria was S. aureus (37.3%),
followed by E .coli (25.4%) and Klebsiella species (13.6%). All bacterial isolates were resistant to
at least one antibiotic, and 86.4 % were resistant to more than one antibiotic (multiple drug
resistance).
Conclusion: Single and multiple drug resistance to the commonly used antibiotics in the study
area was found to be very high leaving clinicians with a very few choices of drugs for the
treatment of post surgical wound infected patients. Therefore, it is critical that use of antimicrobial
agents with in hospitals, public healthcare providers as well as private ones should be reviewed
and further studies to find out the overall resistance patterns and their possible causes and
associated factors in the region at large need to be carried out. |
| URI: | http://hdl.handle.net/123456789/2578 |
| Appears in: | Thesis - Medical Microbiology
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