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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/2282

Title: SYNDROMIC MANAGEMENT APPROACH AND LABORATORY DIAGNOSIS OF TRICHOMONAS VAGINALIS IN STI COMPLIANT AND PREGNANT WOMEN ATTENDING MERAWI HEALTH CENTER, MERAWI, AMHARA REGIONAL STATE, ETHIOPIA:
Authors: Muluneh, AdeMe
Advisors: Tadesse Kebede: - [PhD fellow, MSc.]
Nigus Fikrie: - [PhD fellow, MSc.]
Keywords: STI
Syndromic Management approach
Trichomoniasis
Copyright: May-2011
Date Added: 3-May-2012
Publisher: AAU
Abstract: Back ground: Trichoomonas vaginalis is a flagellated, single cell protozoan parasite. T. vaginalis carries the distinction of being the only truly sexually transmitted parasitic infection in humans. It is highly adapted to the human urogenital tract and majority of infections are asymptomatic. Symptomatic trichomoniasis presents with an offensive vaginal discharge and vulval itching in women. T. vaginalis infection has been shown to be associated with adverse pregnancy outcomes, particularly premature rupture of membranes, pre-term delivery and low birth weight. Objective: the aim of this study was to determine the prevalence of T. vaginalis among STI compliant and (or) pregnant women attending Merawi Health center. Simultaneous comparison of the laboratory (wet mount microscopy) result with the syndromic management results was performed. Result: 222 women have participated in this study. 198 were pregnant and 24 were STI complaint. Majority of them were under the age group of 15-25 years (48.6%, 108). 73.9% (164) were illiterate, 94.1% (209) were married, and 86.9% (193) didn’t have awareness to any of STIs. Syndromic management approach has identified 4 women (1.8%) who had self-reported symptoms related to trichomoniasis. However; the laboratory wet mount diagnosis has identified 14 women who were positive for the trophozoites of T. vaginalis. As a result, the prevalence of trichomoniasis using the laboratory wet mount result was increased to 6.3% (14/222). The sensitivity of syndromic management approach with respect to the wet microscopy was 21.4%. Conclusion: As a result of high rates of asymptomatic infections, syndromic management approach should not be the first choice to screen out trichomoniasis. So, this study supports the need for improved diagnostic parameters and disease control activities to reduce adverse trichomoniasis associated reproductive health outcomes such as ectopic pregnancy, low infant birth weight and preterm labor.
URI: http://hdl.handle.net/123456789/2282
Appears in:Thesis - Medical Parasitology

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