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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/2214

Advisors: Dr. Gizachew alemayehu
Copyright: Jun-2010
Date Added: 3-May-2012
Abstract: Abstract Natural products have been in use since ancient times as medicines insecticides, natural dyes and spices, and the use of herbal remedies and dietary supplements (Cowan MM. 1999). It was estimated that about 80% of all the world medicines are originally derived from plant sources, especially those found in tropical regions. However, many of the plants with in these often remote regions of the world have yet to be identified as species and only about 15% of the known angiosperm species in this region were examined for their medicinal potential. Therefore, there are most definitely a large number of plants derived medicines and other useful compounds that have to be discovered and characterized around the world (Cseke, H., et al., 2006). Therefore, plant secondary metabolites are currently the subject of much research interest but their extraction as part of phytochemical or biological investigations presents specific challenges that must be addressed through out the solvent extraction process. Successful extraction begins with careful selection and preparation of plant samples, and thorough review of the appropriate literature for indications of which protocols are suitable for particular classes of compounds or plant species. During extraction of plant materials it is important to minimize interference from compounds that may be co-extracted with the target compounds, and to avoid contamination of the extract, as well as to prevent decomposition of important metabolites or artifact formation as a result of extraction conditions or solvent impurities (William, P., et al.).
URI: http://hdl.handle.net/123456789/2214
Appears in:Thesis - Chemistry

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