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http://hdl.handle.net/123456789/1926
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| Title: | SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF TRIPHENYLTINBENZOATE ANILINE COMPLEX |
| Authors: | Berhan, Zewdie |
| Advisors: | Prof. M.K. Choudhury |
| Copyright: | 2008 |
| Date Added: | 20-Jan-2009 |
| Publisher: | Addis Ababa University |
| Abstract: | Abstract
Triphenyltinbenzoate and triphenyltinbenzoate aniline complex had been
synthesized and characterized on the basis of infrared, mass and nuclear
magnetic resonance (1H and 13C) spectral studies. The synthesized compounds
had sharp melting point which indicated the purity of the compounds.
The antimicrobial activities of the synthesized compounds were tested against six
different pathogenic microorganisms; Escherichia coli, Pseudomonas
aeruginosa, Staphylococcus aureus, Streptococcus pyogenes, Aspergillus niger
and Candida ablicans in vitro. The results indicated that the synthesized
compounds exhibit a higher activity against Escherichia coli, Streptococcus
pyogenes, Pseudomonas aeruginosa and Candida ablicans than the starting
compound. The results also indicated that the compounds did not exhibit any
activity against Aspergillus niger at concentration as high as 200 μgml-1 |
| Description: | A thesis submitted to the School of Graduate Studies of
Addis Ababa University in partial fulfillment of the
requirements for the degree of Master of Science in
Pharmaceutical Analysis and Quality Assurance |
| URI: | http://hdl.handle.net/123456789/1926 |
| Appears in: | Thesis - Chemistry
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