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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1210

Title: STUDIES ON FIRST ROWTRANSITION METAL COMPLEXES DERIVED FROM NINHYDRIN AND AMINO ACIDS HAVING POLAR(THREONINE) AND NONPOLAR(LEUCINE) SIDE CHAINS
Authors: Negash, Getachew
Advisors: Dr. Yonas Chebude, Advisor
Keywords: metal complexes, Schiff base, ninhydrin, Ruhmann’s purple, – Leucine, –L–Threonine and antimicrobial activity.
Copyright: 2003
Date Added: 23-May-2008
Publisher: Addis Ababa university
Abstract: Abstract . Complexes of Co(II), Ni(II), and Zn(II) with Ruhmann’s purple, those of Fe(III) and Mn(II) with an intermediate Schiff base ( ketimine and / or aldimine) and Cu(II) with ninhydrin were successfully synthesized. All complexes were distinctly colored and stable to atmospheric conditions. The complexes were characterized by elemental analysis, molar conductance, magnetic susceptibility, infrared and electronic spectral studies. The ligands were shown to behave as a monobasic tridentate ONO, bidentate ON or OO donor. The complexes of Zn(II), Co(II) and Ni(II) are purely Ruhmann’s purple, those of Mn(II) and Fe(III) are Schiff base (ketimine), Schiff base and ninhydrin or Schiff base and Ruhmann’s purple complexes. An octahedral geometry is proposed for all of the metal complexes, except Mn(II). A comparative anti- microbial study of the complexes was undertaken against two gram - negative bacteria, Escherichia coli and one gram - positive bacterium Staphylococcus aureus. It was revealed that except Cu(II) and to some extent Zn(II) complexes most of the complexes exhibit a reduced activity against both bacterium.
Description: A Thesis Presented to Office of Research and Graduate Programs Addis Ababa University In Partial Fulfillment of the Requirements for the Degree of Master of Science in Chemistry
URI: http://hdl.handle.net/123456789/1210
Appears in:Thesis - Medical Microbiology

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